需要随访或积极治疗的结直肠癌患者的患病率。

Prevalence of patients with colorectal cancer requiring follow-up or active treatment.

作者信息

Chauvenet Marion, Lepage Côme, Jooste Valérie, Cottet Vanessa, Faivre Jean, Bouvier Anne-Marie

机构信息

Registre Bourguignon des Cancers Digestifs, Inserm U866, Université de Bourgogne, CHU Dijon, Dijon F-21079, France.

出版信息

Eur J Cancer. 2009 May;45(8):1460-5. doi: 10.1016/j.ejca.2009.01.012. Epub 2009 Feb 11.

DOI:10.1016/j.ejca.2009.01.012

PMID:19216071

Abstract

INTRODUCTION

The objective of this study was to estimate prevalence of colorectal cancers requiring care or follow-up.

MATERIALS AND METHODS

Prevalence was observed in 2005 on the population-based digestive cancer registry of Burgundy (France). Total and 5-year partial prevalences were calculated. The prevalence of patients requiring follow-up was estimated using non-mixture cure models. The prevalence of patients with recurrence was estimated using annual recurrence rates.

RESULTS

Total prevalence was 262,244 cases in France. The mean variation in 5-year partial prevalence between successive 5-year periods was +8.0%. Time to cure was estimated to be 9.3 years, suggesting that follow-up is needed over a 10-year period, corresponding to 71.7% of prevalent cases. In 2005, 5.4% of prevalent cases had recurrent cancer requiring treatment.

CONCLUSION

This study underlines the burden of colorectal cancer on the health system. Prevalence of patients requiring follow-up or treatment provides interesting information in addition to classic indicators.

摘要