Borowitzka L J, Volcani B E
Arch Microbiol. 1977 Mar 1;112(2):147-52. doi: 10.1007/BF00429327.
Levels of the cyclic nucleotides, cAMP and cGMP, were determined in four species of pennate diatoms; changes in their levels and ratios were monitored in silicon-starved and light-dark synchronized cultures of Cylindrotheca fusiformis. Content of both cAMP and cGMP changed during the cell cycles: when silicate was added to starved cultures, cAMP, cGMP and DNA levels rose rapidly; cAMP and cGMP declined befor DNA synthesis was complete and continued to fall during the events leading to cell separation. In unstarved synchronies, net synthesis of DNA continued until cell separation; 1 h before cell separation cAMP levels fell while those of cGMP rose. The results support of the proposal that cAMP and cGMP may play a part in the process of cell division in the diatom, possible involving silicon.
测定了四种羽纹硅藻中环核苷酸cAMP和cGMP的水平；在硅饥饿和光暗同步培养的梭形筒柱藻中监测了它们水平和比例的变化。cAMP和cGMP的含量在细胞周期中均发生变化：当向饥饿培养物中添加硅酸盐时，cAMP、cGMP和DNA水平迅速上升；在DNA合成完成之前，cAMP和cGMP下降，并在导致细胞分离的过程中持续下降。在未饥饿的同步培养中，DNA的净合成一直持续到细胞分离；在细胞分离前1小时，cAMP水平下降而cGMP水平上升。这些结果支持了cAMP和cGMP可能在硅藻细胞分裂过程中发挥作用的提议，可能涉及硅。
