Brooks John K, Ahmad Rizwan
Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201-1586, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Mar;107(3):e32-5. doi: 10.1016/j.tripleo.2008.11.023.
The oculocerebrorenal syndrome of Lowe (OCRL) is a rare X-linked recessive disorder, chiefly characterized by ocular involvement, mental retardation, and kidney disease. A literature review is provided, detailing the diversity of oral anomalies associated with the OCRL syndrome. Reported abnormalities include delayed tooth eruption, odontogenic cyst formation, and constricted dental arches. In addition, we present an unusual case of an 18-year-old male affected with the OCRL syndrome and fetal alcohol syndrome. The oral radiographic examination was significant for multiple impacted permanent teeth, many with pericoronal radiolucencies, and an underdeveloped mandible.
洛氏眼脑肾综合征（OCRL）是一种罕见的X连锁隐性疾病，主要特征为眼部病变、智力发育迟缓及肾脏疾病。本文提供一篇文献综述，详述与OCRL综合征相关的口腔异常的多样性。报告的异常情况包括牙齿萌出延迟、牙源性囊肿形成及牙弓狭窄。此外，我们呈现一例18岁男性的特殊病例，该患者同时患有OCRL综合征和胎儿酒精综合征。口腔X线检查显示多颗恒牙阻生，许多伴有冠周透射区，且下颌骨发育不全。
