Croche Santander B, Porras González A, Madrid Castillo M D, Fernández Fernández M A, Obando Santaella I
Hospital Infantil Universitario Virgen del Rocío, Sevilla, España.
An Pediatr (Barc). 2009 Feb;70(2):168-72. doi: 10.1016/j.anpedi.2008.09.013. Epub 2009 Feb 3.
Intracranial complications (ICC) secondary to otitis media are unusual but potentially life-threatening. We report an unusually high frequency of these events, and describe their clinical and epidemiological features.
A retrospective study of all pediatric patients with ICC admitted to our tertiary hospital from April 2004 to November 2007.
Eight patients had ICC: Sigmoid sinus thrombosis (4), lateral sinus thrombosis (1), meningitis (2), epidural abscess (1), otitic hydrocephalus (1). Four of the patients had acute mastoiditis. Pre-admission oral antibiotics were administered in 87.5% of the patients. Fever, otalgia, headache and VI and VII cranial nerves paralysis were the most frequent symptoms associated. The microorganism could be isolated in 3 patients: S pyogenes (2) and P mirabilis (1); the remaining patients had negative cultures. All of the patients received broad-spectrum parenteral antibiotics and 2 of them underwent a radical mastoidectomy.
We report an unusually high incidence of cranial complications secondary to acute otitis media. Multicenter studies are needed in order to assess whether there is an increase in the incidence of these events.
中耳炎继发的颅内并发症(ICC)并不常见,但可能危及生命。我们报告了这些事件异常高的发生率,并描述了其临床和流行病学特征。
对2004年4月至2007年11月入住我院三级医院的所有患有ICC的儿科患者进行回顾性研究。
8例患者患有ICC:乙状窦血栓形成(4例)、外侧窦血栓形成(1例)、脑膜炎(2例)、硬膜外脓肿(1例)、耳源性脑积水(1例)。4例患者患有急性乳突炎。87.5%的患者在入院前使用了口服抗生素。发热、耳痛、头痛以及第VI和第VII颅神经麻痹是最常见的相关症状。3例患者可分离出微生物:化脓性链球菌(2例)和奇异变形杆菌(1例);其余患者培养结果为阴性。所有患者均接受了广谱肠外抗生素治疗,其中2例接受了根治性乳突切除术。
我们报告了急性中耳炎继发颅内并发症的异常高发生率。需要进行多中心研究以评估这些事件的发生率是否有所增加。