Singh Jasvinder A, Schmitz Katherine H, Petit Moira A
Minneapolis VA Medical Center, Rheumatology, One Veterans Drive, Minneapolis, 55417 MN, USA.
Joint Bone Spine. 2009 May;76(3):273-80. doi: 10.1016/j.jbspin.2008.07.016. Epub 2009 Feb 13.
To assess the effect of 9 months of strength training on total body and regional bone mineral density (BMD, g/cm(2)) in 58 premenopausal women aged 30-50 years.
Participants were randomized to either twice weekly supervised strength training for 15 weeks followed by 24 weeks of unsupervised training (treatment group) or control group. Height, weight, maximal muscular strength, nutrient intake and physical activity were assessed. Total body dual energy X-ray absorptiometry (DXA, Lunar Prodigy) scans were taken and analyzed for body composition (lean and fat mass), and BMD for total body and its sub-regions (spine, hip, arms and legs). All measurements were performed at baseline, 15 and 39 weeks. Analysis of covariance was used to assess group differences in BMD change adjusted for baseline BMD, weight, energy and calcium intake.
At baseline, the two groups had similar BMD and body size characteristics ( P<0.05 for all), except that the treatment group had lower body weight (-7.1 kg), and higher energy (+259 kJ/d) and calcium (+232 mg/d) intake at baseline. Adjusted % change in BMD over 15 weeks (0.5% vs. 0.4%) or 39 weeks (0.9% vs. 1.2%) did not differ significantly between the exercise and control groups, respectively. The exercise group increased BMD at the spine and legs (1-2.2%), while there was no change in the controls, but differences between groups were not significant.
Strength training over 9 months did not lead to significantly greater change in total body or regional BMD in premenopausal women.
评估9个月的力量训练对58名年龄在30至50岁之间的绝经前女性全身及局部骨矿物质密度（BMD，克/平方厘米）的影响。
参与者被随机分为两组，一组接受为期15周、每周两次的有监督力量训练，随后进行24周的无监督训练（治疗组），另一组为对照组。评估了身高、体重、最大肌肉力量、营养摄入和身体活动情况。采用全身双能X线吸收法（DXA，Lunar Prodigy）扫描并分析身体成分（瘦体重和脂肪量）以及全身及其子区域（脊柱、髋部、手臂和腿部）的骨矿物质密度。所有测量均在基线、第15周和第39周进行。采用协方差分析评估在根据基线骨矿物质密度、体重、能量和钙摄入量进行调整后，两组在骨矿物质密度变化方面的差异。
在基线时，两组的骨矿物质密度和身体尺寸特征相似（所有P<0.05），但治疗组在基线时体重较低（-7.1千克），能量摄入量较高（+259千焦/天），钙摄入量较高（+232毫克/天）。运动组和对照组在15周（0.5%对0.4%）或39周（0.9%对1.
