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血液透析患者更喜欢肾特异性口服营养补充剂还是标准口服营养补充剂?

Do hemodialysis patients prefer renal-specific or standard oral nutritional supplements?

作者信息

Williams Rosalind F, Summers Angela M

机构信息

Dietetics Department, Manchester Royal Infirmary, Manchester, England, United Kingdom.

出版信息

J Ren Nutr. 2009 Mar;19(2):183-8. doi: 10.1053/j.jrn.2008.11.011.

DOI:10.1053/j.jrn.2008.11.011
PMID:19218047
Abstract

OBJECTIVE

We investigated whether hemodialysis (HD) patients prefer standard or renal-specific oral nutritional supplements (ONS).

DESIGN

Standard ONS Fortisip (Nutricia Clinical Care, Wiltshire, Trowbridge, UK) and renal ONS Renilon (Nutricia Clinical Care) and Nepro (Abbott Laboratories, Ltd., Maidenhead, Berkshire, UK) were compared using single-blind taste tests and face-to-face, interviewer-administered questionnaires.

SETTING

This study took place in our HD unit in September 2007.

PATIENTS

There were 40 patients, including 24 males, 14 smokers, and 26 Caucasians, aged <30 years (n = 6), 31 to 50 years (n = 13), 51 to 70 years (n = 12), and >70 years (n = 9).

INTERVENTION

Patients ranked ONS taste on a Likert scale (1 to 5), and compared flavor options, phosphate-binder requirements, and fluid contribution.

MAIN OUTCOME MEASURE

Which factors influenced a patient's choice of ONS?

RESULTS

Gender, smoking status, ethnicity, and age influenced patients' choices. The taste of Fortisip and Nepro was liked by 58% (n = 23), versus 28% liking Renilon (n = 11). Renilon was disliked by 35% (n = 14), Nepro was disliked by 30% (n = 12), and Fortisip was disliked by 25% (n = 10). The favorite taste was Fortisip, in 52% (n = 21). However, 21% (n = 4) who preferred the taste of renal ONS would not choose them long-term because of their limited flavor ranges. The lack of phosphate binders with Renilon was a deciding factor in 27% (n = 19/33). The low fluid contribution of renal ONS influenced the choice of 43% (n = 12/28). All factors considered, standard ONS remained most popular for patients aged >70 years. However, in all other subgroups, and particularly males and non-Caucasians, renal ONS became more popular. Many patients (23%; n = 9) would sacrifice taste for the benefits of renal ONS.

CONCLUSIONS

Renal ONS are more popular in HD patients because of their low fluid contribution and phosphate-binder requirements, which can influence preference over taste. Patients need information to make informed choices.

摘要

目的

我们调查了血液透析(HD)患者更喜欢标准型还是肾特异性口服营养补充剂(ONS)。

设计

使用单盲味觉测试以及由访谈者当面发放的问卷,对标准ONS产品Fortisip(纽迪希亚临床护理公司,英国威尔特郡特罗布里奇)、肾用ONS产品Renilon(纽迪希亚临床护理公司)和Nepro(雅培实验室有限公司,英国伯克郡梅登黑德)进行比较。

地点

本研究于2007年9月在我们的血液透析科室开展。

患者

共有40名患者,其中男性24名,吸烟者14名,白种人26名,年龄小于30岁的有6名,31至50岁的有13名,51至70岁的有12名,大于70岁的有9名。

干预措施

患者按照李克特量表(1至5)对ONS的味道进行排名,并比较口味选择、磷结合剂需求和液体含量。

主要观察指标

哪些因素会影响患者对ONS的选择?

结果

性别、吸烟状况、种族和年龄会影响患者的选择。58%(n = 23)的患者喜欢Fortisip和Nepro的味道,而喜欢Renilon味道的患者占28%(n = 11)。35%(n = 14)的患者不喜欢Renilon,30%(n = 12)的患者不喜欢Nepro,25%(n = 10)的患者不喜欢Fortisip。最喜欢的味道是Fortisip,占52%(n = 21)。然而,21%(n = 4)喜欢肾用ONS味道的患者不会长期选择它们,因为其口味种类有限。Renilon缺乏磷结合剂是27%(n = 19/33)患者做出决定的因素。肾用ONS液体含量低影响了四成三(n = 12/28)患者的选择。综合所有因素考虑,标准ONS在70岁以上的患者中仍然最受欢迎。然而,在所有其他亚组中,尤其是男性和非白种人中,肾用ONS更受欢迎。许多患者(23%;n = 9)会为了肾用ONS的益处而牺牲味道。

结论

肾用ONS在HD患者中更受欢迎,因为其液体含量低且对磷结合剂需求少,这些因素可能比味道更能影响患者的偏好。患者需要信息以便做出明智的选择。

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