Inaba Hidefumi, Suzuki Satoru, Shigematsu Satoshi, Kobayashi Satoshi, Nishio Shin-ichi, Hashizume Kiyoshi
Department of Aging Medicine and Geriatrics, Shinshu University, Graduate School of Medicine, Matsumoto.
Intern Med. 2009;48(4):225-9. doi: 10.2169/internalmedicine.48.1583. Epub 2009 Feb 16.
Central nervous system (CNS) sarcoidosis is a crucial disease and has a poor prognosis. A 58-year-old woman had acute development of polydipsia and polyuria. Her pituitary MRI demonstrated a swelling of pituitary gland and hypophyseal stalk. She was diagnosed as central diabetes insipidus (CDI) due to CNS sarcoidosis based on the examinations and pituitary MRI findings as well as a result of cutaneous biopsy. Uveitis and bilateral hilar lymphadenopathy were observed mildly throughout. However, CDI and pituitary MRI findings were getting recovered spontaneously without steroid treatment in a couple of months, suggesting an atypical clinical course of CNS sarcoidosis.
中枢神经系统（CNS）结节病是一种严重疾病，预后较差。一名58岁女性出现急性烦渴和多尿症状。她的垂体磁共振成像（MRI）显示垂体和垂体柄肿胀。根据检查结果、垂体MRI表现以及皮肤活检结果，她被诊断为中枢神经系统结节病所致的中枢性尿崩症（CDI）。整个过程中轻度观察到葡萄膜炎和双侧肺门淋巴结肿大。然而，在几个月内，未经类固醇治疗，CDI和垂体MRI表现自行恢复，提示中枢神经系统结节病的非典型临床病程。
