Sedlmaier B, Pomorzev A, Haisch A, Halleck P, Scherer H, Göktas O
Ear, Nose & Throat Clinic and Polyclinics, Charité Campus Mitte, School of Medicine Berlin, Berlin, Germany.
Lasers Med Sci. 2009 Sep;24(5):793-800. doi: 10.1007/s10103-009-0646-7. Epub 2009 Feb 14.
A long-lasting dysfunction of the eustachian tube seems to be the etiologic origin for development of chronic otitis media (COM) with mesotympanic perforation, otitis media with effusion (OME), and chronic atelectasis of the middle ear. Surgical interventions in the middle ear generally treat the sequelae of the tube dysfunction but not the dysfunction itself. This prospective clinical study investigated how far fiber-guided laser ablation of the posterior half of the epipharyngeal tubal ostium led to better middle ear ventilation in the otologic disease patterns mentioned below. There were 38 adult patients included in the analysis. The patients in one group had a perforated tympanic membrane [COM before primary tympanoplasty (n = 14) or revision tympanoplasty (n = 5)]; the patients in a second group had an intact eardrum [OME resistant to therapy (n = 3), with an atelectasis of the middle ear (n = 2) or problems of pressure equalization with fast changes in ambient pressure (diving, flying) (n = 14)]. Laser ablation of the posterior half of the epipharyngeal tubal ostium was performed, generally with local anesthesia, if tubal function testing was pathologic (Valsalva maneuver, passive tube opening, tympanogram). In patients with COM the procedure was performed 8 weeks before the middle ear surgery. All patients were checked 8 weeks postoperatively and in the course of the following year. The intervention seemed to have had a positive effect on tube function in 68.4% of patients operated on (P = 0.001). In 26 of the 38 patients that had undergone operation, an improvement the results of tubal function tests could be seen in the postoperative follow-up. In the COM group the Valsalva maneuver improved in 14 of 19 patients (73.6%) (P = 0.001), and the passive tube opening improved in nine of 18 patients (50%). In the group with an intact eardrum the Valsalva maneuver improved in 13 of 18 patients (72.2%) (P = 0.001). The resulting condition remained stable after 1 year. None of the patients showed any complications as a result of the therapy. Minimally invasive shaping of the distal eustachian tube under topical anesthesia can be recommended for patients with the above-mentioned diagnoses who have pathologic middle ear ventilation. Especially prior to tympanoplasties, and especially in otologic revision procedures, where middle ear ventilation is a prerequisite for successful otologic surgery, the function of the eustachian tube can be optimized in 70% of the patients, particularly if there are pathological findings (tubal tonsil, narrow orifice of the tubal ostium, adenoids). The placement of permanent ear tubes in adults with recurrent OME can also be avoided by the procedure described. The resultant conditions remained stable for the next year. Patients with tympanic ventilation problems due to rapid pressure changes (flying, diving) can also benefit from this procedure.
咽鼓管的长期功能障碍似乎是导致中鼓室穿孔的慢性中耳炎(COM)、中耳积液(OME)和中耳慢性肺不张的病因。中耳的手术干预通常治疗咽鼓管功能障碍的后遗症,而不是功能障碍本身。这项前瞻性临床研究调查了纤维引导的咽鼓管咽口后半部激光消融在多大程度上能改善以下耳科疾病模式中的中耳通气。分析纳入了38例成年患者。一组患者鼓膜穿孔[初次鼓膜成形术之前的COM(n = 14)或翻修鼓膜成形术(n = 5)];第二组患者鼓膜完整[对治疗耐药的OME(n = 3)、伴有中耳肺不张(n = 2)或在环境压力快速变化(潜水、飞行)时存在压力平衡问题(n = 14)]。如果咽鼓管功能测试结果异常(瓦尔萨尔瓦动作、被动咽鼓管开放、鼓室图),一般在局部麻醉下对咽鼓管咽口后半部进行激光消融。对于COM患者,该手术在中耳手术前8周进行。所有患者在术后8周及接下来的一年中接受检查。该干预措施似乎对68.4%接受手术的患者的咽鼓管功能产生了积极影响(P = 0.001)。在接受手术的38例患者中,有26例在术后随访中咽鼓管功能测试结果得到改善。在COM组中,19例患者中有14例(73.6%)瓦尔萨尔瓦动作得到改善(P = 0.001),18例患者中有9例(50%)被动咽鼓管开放得到改善。在鼓膜完整的组中,18例患者中有13例(72.2%)瓦尔萨尔瓦动作得到改善(P = 0.001)。1年后病情保持稳定。没有患者因该治疗出现任何并发症。对于上述诊断且中耳通气异常的患者,可推荐在局部麻醉下对咽鼓管远端进行微创塑形。特别是在鼓膜成形术之前,尤其是在耳科翻修手术中,中耳通气是耳科手术成功的前提条件,在70%的患者中,咽鼓管功能可得到优化,特别是存在病理表现(咽鼓管扁桃体、咽鼓管咽口狭窄或腺样体)时。通过所描述的手术还可避免对复发性OME成年患者放置永久性耳管。在接下来的一年中病情保持稳定。因压力快速变化(飞行、潜水)导致鼓膜通气问题的患者也可从该手术中获益。