Semple Shirley J, Strathdee Steffanie A, Zians Jim, Patterson Thomas L
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093-0680, USA.
Am J Addict. 2009 Jan-Feb;18(1):65-72. doi: 10.1080/10550490802544466.
This study examined the association between sexual risk behavior and co-administration of methamphetamine with other drugs in a sample of 341 HIV-positive MSM. Those who reported methamphetamine co-administration in the past two months (65%) reported significantly more unprotected anal and oral sex and a greater number of casual, anonymous, and paid sex partners in this timeframe compared to men who used methamphetamine alone. Two primary patterns of co-administration were identified: 1) drug combinations motivated by sexual performance and enhancement (eg, methamphetamine, poppers, sildenafil); and 2) "party drug" combinations (eg, methamphetamine, GHB, ketamine). Implications for further research and possible applications to risk-reduction interventions are discussed.
本研究在341名HIV阳性男男性行为者样本中,考察了性风险行为与甲基苯丙胺与其他药物联合使用之间的关联。在过去两个月内报告过联合使用甲基苯丙胺的人(65%),与单独使用甲基苯丙胺的男性相比,在这一时间段内报告的无保护肛交和口交显著更多,且有更多的临时性、匿名性和付费性伴侣。确定了两种主要的联合用药模式:1)出于性表现和增强性欲动机的药物组合(如甲基苯丙胺、Poppers、西地那非);2)“派对药物”组合(如甲基苯丙胺、γ-羟基丁酸、氯胺酮)。文中讨论了对进一步研究的启示以及在降低风险干预措施中的可能应用。