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铥:钇铝石榴石激光前列腺切除术治疗难治性尿潴留男性患者。

Thulium:yttrium-aluminium-garnet laser prostatectomy in men with refractory urinary retention.

作者信息

Bach Thorsten, Herrmann Thomas R W, Haecker Axel, Michel Maurice S, Gross Andreas

机构信息

Department of Urology, University Hospital Mannheim, Mannheim, Germany.

出版信息

BJU Int. 2009 Aug;104(3):361-4. doi: 10.1111/j.1464-410X.2009.08412.x. Epub 2009 Feb 11.

DOI:10.1111/j.1464-410X.2009.08412.x
PMID:19220261
Abstract

OBJECTIVE

To evaluate the feasibility and efficacy of thulium:yttrium-aluminium-garnet (YAG) laser prostatectomy in patients with an indwelling transurethral catheter due to recurrent urinary retention secondary to benign prostatic obstruction.

PATIENTS AND METHODS

Preoperative data and postoperative outcome, as well as complications, were recorded in 65 patients with a history of recurrent urinary retention before surgery (group A), who were compared with a group of 143 men with no recurrent urinary retention (group B).

RESULTS

The mean (sd) volume of the prostate was 45.6 (22.5) and 43.1 (24.5) mL in groups A and B, respectively. The respective preoperative prostate-specific antigen levels were 3.6 (7.8) and 2.8 (6.4) ng/mL, the surgical duration 72.4 (28.9) and 65.6 (28.6) min, the mean laser time and energy 32.5 (11.8) min/140.7 (42.1) kJ and 29.4 (11.6) min/117.6 (11.6) kJ, the maximum urinary flow rate after surgery 19.6 (11.2) and 19.1 (9.6) mL/s, and the postvoid residual urine volume 26.7 (36.3) and 20.6 (27.3) mL. Recorded complications were: bleeding, at 3% in group A and 1.4% in group B; urinary tract infection 15.4% and 4.2%; and a second procedure, 3% and 2.3%. Overall, complications were more frequent in group A (P = 0.02).

CONCLUSION

Thulium:YAG prostatectomy is feasible and effective, even in patients with potentially impaired detrusor function. The long-term durability of these promising results has yet to be confirmed.

摘要

目的

评估因良性前列腺梗阻继发反复尿潴留而留置经尿道导管的患者行铥:钇铝石榴石(YAG)激光前列腺切除术的可行性和疗效。

患者与方法

记录65例术前有反复尿潴留病史的患者(A组)的术前数据、术后结果及并发症,并与143例无反复尿潴留的男性患者(B组)进行比较。

结果

A组和B组前列腺的平均(标准差)体积分别为45.6(22.5)和43.1(24.5)mL。术前前列腺特异性抗原水平分别为3.6(7.8)和2.8(6.4)ng/mL,手术时间分别为72.4(28.9)和65.6(28.6)分钟,平均激光时间和能量分别为32.5(11.8)分钟/140.7(42.1)kJ和29.4(11.6)分钟/117.6(11.6)kJ,术后最大尿流率分别为19.6(11.2)和19.1(9.6)mL/s,排尿后残余尿量分别为26.7(36.3)和20.6(27.3)mL。记录的并发症有:出血,A组为3%,B组为1.4%;尿路感染分别为15.4%和4.2%;二次手术分别为3%和2.3%。总体而言,A组并发症更常见(P = 0.02)。

结论

铥:YAG前列腺切除术是可行且有效的,即使在逼尿肌功能可能受损的患者中也是如此。这些 promising 结果的长期持久性还有待证实。 (注:此处“promising”未翻译准确,可译为“有前景的”)

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