Medici M C, Morelli A, Arcangeletti M C, Calderaro A, De Conto F, Martinelli M, Abelli L A, Dettori G, Chezzi C
Section of Microbiology, Department of Pathology and Laboratory Medicine, University Medical School, Parma, Italy.
Clin Microbiol Infect. 2009 Jan;15(1):97-100. doi: 10.1111/j.1469-0691.2008.02117.x.
On December 2006, an outbreak of gastroenteritis occurred at a residential-care facility for the elderly in northern Italy. Thirty-five of 61 individuals interviewed (attack rate, 57.4%) fell ill. In 94.3% of cases, the onset of illness was within 48 h of a Christmas party at the facility. Norovirus (NoV) was detected by RT-PCR in 24 of 31 individuals examined, including three asymptomatic food-handlers, in whom there was evidence of long-lasting excretion of viral particles. The identification of a sequence referring to the '2006a GII.4 NoV variant' in all examined strains supported the hypothesis of a common point source. This retrospective cohort study is the first report on an outbreak of NoV gastroenteritis in an Italian residential-care facility for the elderly.
2006年12月，意大利北部一家老年护理机构爆发了肠胃炎。接受访谈的61人中，有35人患病（发病率为57.4%）。在94.3%的病例中，发病时间在该机构举办圣诞派对后的48小时内。通过逆转录聚合酶链反应（RT-PCR）在31名接受检查的人员中检测到24人感染诺如病毒（NoV），其中包括三名无症状的食品处理人员，有证据表明他们长期排出病毒颗粒。在所有检测菌株中均鉴定出与“2006a GII.4 NoV变异株”相关的序列，这支持了共同传染源的假设。这项回顾性队列研究是关于意大利一家老年护理机构诺如病毒肠胃炎爆发的首份报告。
