Department of Clinical Pharmacology and Drug Optimisation Clinic, Adelaide, South Australia, Australia.
Intern Med J. 2009 Sep;39(9):595-9. doi: 10.1111/j.1445-5994.2008.01820.x. Epub 2008 Nov 3.
The aims of this study were to determine the documentation of pharmacotherapy optimization goals in the discharge letters of patients with the principal diagnosis of chronic heart failure.
A retrospective practice audit of 212 patients discharged to the care of their local general practitioner from general medical units of a large tertiary hospital. Details of recommendations regarding ongoing pharmacological and non-pharmacological management were reviewed. The doses of medications on discharge were noted and whether they met current guidelines recommending titration of angiotensin-converting enzyme inhibitors and beta-blockers. Ongoing arrangements for specialist follow up were also reviewed.
The mean age of patients whose letters were reviewed was 78.4 years (standard deviation +/- 8.6); 50% were men. Patients had an overall median of six comorbidities and eight regular medications on discharge. Mean length of stay for each admission was 6 days. Discharge letters were posted a median of 4 days after discharge, with 25% not posted at 10 days. No discharge letter was sent in 9.4% (20) of the cases. Only six (2.8%) letters had any recommendations regarding future titration of angiotensin-converting enzyme inhibitors and 6.6% (14) for beta-blockers. Recommendations for future non-pharmacological management, for example, diuretic action plans, regular weight monitoring and exercise plans were not found in the letters in this audit.
Hospital discharge is an opportunity to communicate management plans for treatment optimization effectively, and while this opportunity is spurned, implementation gaps in the management of cardiac failure will probably remain.
本研究旨在确定慢性心力衰竭主要诊断患者出院病历中药物治疗优化目标的记录情况。
对一家大型教学医院综合医疗病房 212 名出院患者的病历进行回顾性实践审核。审核了有关持续药物和非药物治疗管理建议的详细信息。记录了出院时药物的剂量,并评估其是否符合目前推荐的血管紧张素转换酶抑制剂和β受体阻滞剂滴定的指南。同时还审核了专科随访的持续安排。
接受审核的患者的平均年龄为 78.4 岁(标准差 +/- 8.6);50%为男性。患者的总体中位共病为 6 种,出院时中位有 8 种常规药物。每次住院的平均住院时间为 6 天。出院后中位 4 天寄出出院病历,25%在 10 天内寄出。9.4%(20 例)的病历未寄出。只有 6 份(2.8%)病历中有关于未来血管紧张素转换酶抑制剂滴定的任何建议,6.6%(14 例)有关于β受体阻滞剂滴定的建议。在本次审核的病历中,未发现有关未来非药物治疗管理(如利尿剂行动计划、定期体重监测和运动计划)的建议。
出院是有效沟通治疗优化管理计划的机会,但如果未能充分利用这一机会,心力衰竭管理中的实施差距可能仍然存在。