非人灵长类动物完全植入式血管通路端口的一种新型替代放置部位和技术。
A novel alternative placement site and technique for totally implantable vascular access ports in non-human primates.
作者信息
Graham Melanie L, Rieke Eric F, Dunning Michele, Mutch Lucas A, Craig Angela M, Zolondek Elizabeth K, Hering Bernhard J, Schuurman Henk-Jan, Bianco Richard W
机构信息
Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN, USA.
出版信息
J Med Primatol. 2009 Jun;38(3):204-12. doi: 10.1111/j.1600-0684.2009.00340.x. Epub 2009 Feb 10.
BACKGROUND
Two novel approaches to implanting a central venous catheter port in non-human primates (NHPs) using peripheral insertion are presented and compared.
METHODS
Sixty vascular access port (VAP) implants were attempted in 52 NHPs by saphenous vein puncture (n = 20) or saphenous vein cutdown (n = 40).
RESULTS
Fifty eight procedures were successful. Eighteen of 20 VAPs were successfully placed using saphenous vein puncture, and 40 of 40 using saphenous vein cutdown. There were no significant differences between procedures. Mean implantation times were similar between groups. At explant or study endpoint, all 58 VAPs were patent.
CONCLUSIONS
Vascular access port implantation by saphenous vein puncture or saphenous vein cutdown is safe and effective in NHPs. It is less invasive than conventional procedures, has fewer complications, provides outstanding patency, and reduces surgery time. Furthermore, it allows for cooperative in-homecage VAP use, minimizing handling stress. We recommend these refined methods for long-term vascular access in NHPs.
背景
介绍并比较了两种使用外周插入法在非人灵长类动物（NHP）中植入中心静脉导管端口的新方法。
方法
通过隐静脉穿刺（n = 20）或隐静脉切开术（n = 40）对52只NHP进行了60次血管通路端口（VAP）植入尝试。
结果
58例手术成功。20个VAP中有18个通过隐静脉穿刺成功植入，40个中有40个通过隐静脉切开术成功植入。各手术方法之间无显著差异。各组的平均植入时间相似。在取出或研究终点时，所有58个VAP均通畅。
结论
在NHP中，通过隐静脉穿刺或隐静脉切开术植入血管通路端口是安全有效的。它比传统手术侵入性小，并发症少，通畅性好，手术时间短。此外，它允许在笼内合作使用VAP，最大限度地减少处理压力。我们推荐这些改进方法用于NHP的长期血管通路。
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