Javitt J C, McBean A M, Nicholson G A, Babish J D, Warren J L, Krakauer H
Worthen Center for Eye Care Research, Washington, D.C.
N Engl J Med. 1991 Nov 14;325(20):1418-22. doi: 10.1056/NEJM199111143252005.
Cross-sectional studies and those using national data sets estimate that glaucoma-related blindness is between six and eight times more common among black Americans than among whites. Community-based studies have found that glaucoma is four to six times more prevalent among blacks. It is not known why blacks with glaucoma are more likely to become blind than whites with glaucoma.
To investigate the possibility that undertreatment of glaucoma is an important factor contributing to this higher rate of blindness, we studied the population-based rates of incisional and laser surgery for open-angle glaucoma among blacks and whites in a 5 percent random sample of Medicare claims for 1986 through 1988.
For all U.S. census divisions combined, the rate of surgery for glaucoma among black Medicare beneficiaries was 2.2 times higher than the rate among white beneficiaries (95 percent confidence interval, 2.1 to 2.3). We calculated an expected rate of treatment among blacks on the basis of the rate of treatment among whites and the assumption that glaucoma is four times more prevalent among blacks--a conservative estimate. The observed rate of glaucoma surgery among blacks was 45 percent lower than the expected rate we calculated, which may in part account for the excess rate of blindness among blacks. The magnitude of this difference in treatment rates varied from 29 percent in the Middle Atlantic states to 50 percent in the South Atlantic states.
Older black Americans are not receiving potentially sight-saving care for open-angle glaucoma at the same rate as older white Americans.
横断面研究以及那些使用全国数据集的研究估计,与青光眼相关的失明在美国黑人中比在白人中普遍六至八倍。基于社区的研究发现,青光眼在黑人中的患病率是白人的四至六倍。尚不清楚为什么患有青光眼的黑人比患有青光眼的白人更容易失明。
为了调查青光眼治疗不足是导致这种较高失明率的一个重要因素的可能性,我们在1986年至1988年医疗保险索赔的5%随机样本中,研究了黑人和白人基于人群的开角型青光眼切开手术和激光手术的发生率。
对于所有合并的美国人口普查区,黑人医疗保险受益人的青光眼手术率比白人受益人高2.2倍(95%置信区间为2.1至2.3)。我们根据白人的治疗率以及青光眼在黑人中的患病率是白人四倍这一假设(保守估计)计算了黑人的预期治疗率。观察到的黑人青光眼手术率比我们计算出的预期率低45%,这可能部分解释了黑人中较高的失明率。治疗率的这种差异幅度从中大西洋各州的29%到南大西洋各州的50%不等。
美国老年黑人接受开角型青光眼潜在视力挽救治疗的比例与美国老年白人不同。