Liu Haipeng, Söderhäll Kenneth, Jiravanichpaisal Pikul
Department of Comparative Physiology, Uppsala University, Norbyvägen 18A, SE-752 36 Uppsala, Sweden.
Fish Shellfish Immunol. 2009 Aug;27(2):79-88. doi: 10.1016/j.fsi.2009.02.009. Epub 2009 Feb 15.
Viral diseases of shrimp have caused negative effects on the economy in several countries in Asia, South America and America, where they have numerous shrimp culture industries. The studies on the immunity of shrimp and other crustaceans have mainly focused on general aspects of immunity and as a consequence little is known about the antiviral responses in crustaceans. The aim of this review is to update recent knowledge of innate immunity against viral infections in crustaceans. Several antiviral molecules have been isolated and characterized recently from decapods. Characterization and identification of these molecules might provide a promising strategy for protection and treatment of these viral diseases. In addition dsRNA-induced antiviral immunity is also included.
对虾的病毒性疾病已在亚洲、南美洲和美洲的多个国家对经济产生了负面影响,这些国家拥有众多对虾养殖产业。对虾及其他甲壳类动物免疫的研究主要集中在免疫的一般方面,因此对甲壳类动物的抗病毒反应了解甚少。本综述的目的是更新有关甲壳类动物针对病毒感染的固有免疫的最新知识。最近已从十足目动物中分离并鉴定了几种抗病毒分子。这些分子的鉴定和表征可能为这些病毒性疾病的预防和治疗提供一个有前景的策略。此外,还包括双链RNA诱导的抗病毒免疫。