Perren A, Schmitt A, Komminoth P, Pavel M
Institut für Pathologie und pathologische Anatomie, Klinikum rechts der Isar, Technische Universität München, München, Deutschland.
Radiologe. 2009 Mar;49(3):198-205. doi: 10.1007/s00117-008-1781-z.
Tumors of the disseminated/diffuse neuroendocrine system (NET) are characterized by a common phenotype. However, the biology varies according to histomorphology, endocrine symptoms and organ of origin. The WHO classification takes these differences into account and uses a common framework, where the parameters size and extent of invasion vary according to the organ of origin. In order to achieve a further standardization of reporting the European Neuroendocrine Tumor Society (ENETS) recently proposed a tumor-node-metastasis (TNM) staging and grading system for gastro-entero-pancreatic NET.
播散性/弥漫性神经内分泌肿瘤（NET）具有共同的表型特征。然而，其生物学特性因组织形态学、内分泌症状及起源器官而异。世界卫生组织（WHO）的分类考虑了这些差异，并采用了一个通用框架，其中肿瘤大小和浸润范围等参数会因起源器官不同而有所差异。为了进一步实现报告的标准化，欧洲神经内分泌肿瘤学会（ENETS）最近提出了一种用于胃肠胰神经内分泌肿瘤的肿瘤-淋巴结-转移（TNM）分期和分级系统。
