Monma Fumihiko, Ueno Satoshi, Yamaguchi Motoko, Tawara Isao, Miyazaki Kana, Nishii Kazuhiro, Nakase Kazunori, Katayama Naoyuki
Department of Hematology and Oncology, Mie University Graduate School of Medicine.
Rinsho Ketsueki. 2009 Jan;50(1):44-8.
A 49-year-old woman with high fever and diffuse swelling of the right cheek was referred to our hospital. Computed tomography showed right orbital tumor with massive involvement. Histopathologic examination of the biopsied right orbital tumor demonstrated extranodal NK/T-cell lymphoma, nasal-type. She was treated with six courses of chemotherapy consisting of etoposide and dexamethasone with 50 Gy of concurrent involved-field radiotherapy. Facial swelling and liver dysfunction improved immediately, and after five courses of chemotherapy, she achieved partial remission without any severe adverse events. L-asparaginase was administered in the final course of chemotherapy. There is no evidence of recurrence 56 months after diagnosis.
一名49岁女性因高热及右侧脸颊弥漫性肿胀被转诊至我院。计算机断层扫描显示右侧眼眶肿瘤伴广泛累及。对活检的右侧眼眶肿瘤进行组织病理学检查,结果显示为鼻型结外NK/T细胞淋巴瘤。她接受了六个疗程的化疗,化疗方案为依托泊苷和地塞米松,并同时进行50 Gy的受累野放疗。面部肿胀和肝功能障碍立即得到改善,经过五个疗程的化疗后,她达到部分缓解,且未出现任何严重不良事件。在化疗的最后一个疗程中使用了L-天冬酰胺酶。诊断后56个月无复发迹象。