Center for Health Services Research in Primary Care, Durham VA Medical Center, Durham, NC 27705, USA.
Int J Geriatr Psychiatry. 2009 Sep;24(9):1010-9. doi: 10.1002/gps.2213.
Depression is often associated with decreased cognitive performance among older adults. The current study focused on the association of neuropsychological functioning and personality traits in depressed and non-depressed older adults.
Data from 75 depressed and 103 non-depressed adults over the age of 60 were analyzed. All participants underwent standardized clinical assessment for depression prior to participation and completed the NEO-PI-R and a series of neuropsychological assessments.
A series of multiple linear regressions were conducted to examine the relationships between personality and neuropsychological performance among depressed and non-depressed older adults. Results indicated that higher Openness to Experience was related to better performance on Parts A and B of the Trail Making Test among depressed older adults, and to better Digit Span Backward performance among all participants. Higher levels of neuroticism were related to poorer performance on Digit Span Backward, but only among depressed older adults. Depressed participants performed more poorly on the Symbol Digit Modalities Test and the Controlled Oral Word Association Test.
Personality characteristics, particularly Openness to Experience, modified the relationship between depression and neuropsychological functioning among older adults. Results indicate that interventions aimed at increasing one's Openness to Experience could potentially attenuate some of the neuropsychological impairments that are associated with depression.
抑郁症常与老年人认知能力下降有关。本研究主要关注抑郁和非抑郁老年人的神经心理学功能和人格特质之间的关系。
对 75 名抑郁和 103 名非抑郁 60 岁以上成年人进行数据分析。所有参与者在参与前都接受了标准化的抑郁临床评估,并完成了 NEO-PI-R 和一系列神经心理学评估。
进行了一系列多元线性回归,以检验抑郁和非抑郁老年人的人格与神经心理学表现之间的关系。结果表明,较高的开放性与抑郁老年人的 Trail Making Test 第 A 部分和第 B 部分表现较好相关,与所有参与者的数字倒背表现较好相关。较高的神经质水平与数字倒背表现较差相关,但仅与抑郁老年人相关。抑郁参与者在符号数字模态测试和受控口头联想测试中的表现较差。
人格特征,特别是开放性,改变了老年人抑郁与神经心理学功能之间的关系。结果表明,旨在增加一个人的开放性的干预措施可能会减轻与抑郁相关的一些神经心理学损伤。