Gómez-García Felipe, Vázquez-Martínez José Luis, Lara-Rodríguez María de los Angeles
Hospital Angeles Mocel, Delegación Miguel Hidalgo, DF México.
Acta Ortop Mex. 2008 Sep-Oct;22(5):292-302.
The prevalence of osteoporosis (OP) in Mexican population is not well known. This disease constitutes a risk factor for fractures due to OP, which result in disability, poor quality of life and increased mortality rates.
To determine prevalence of OP and osteopenia in a group of female health workers from Mexico City using central densitometry (Dual X Ray Absorptiometry-DXA); to compare the Hispanic reference database from the LUNAR DPX L unit vs. the study population; to determine the age at which the peak bone mass is reached and to explore the relationship between some well known factors for osteoporosis and bone mass.
In this prolective, cross-sectional observational study 588 healthy females older than 18 years were selected at different stages and a hip and spine densitometry (DXA) was undertaken with a LUNA DPX L unit. To determine the prevalence of osteoporosis and osteopenia we used the criteria of the Committee of Experts on Osteoporosis from the World Health Organization.
The mean age of our study population was 42.3 years +/- 9.6 (20-65); the weight 66 kg +/- 12.1 (41-139) and height 153.9 cm +/- 5.7 (138-177). The prevalence of osteoporosis on the lumbar spine was 13.5% (IC 95%: 10.5-16) and osteopenia 27.7 (IC 95%: 24-31). On the femoral neck, the prevalence of osteoporosis was 2% (IC 95%: 1.0-3) and osteopenia 26.1% (IC 95%: 22-29). The peak bone mass on the femoral neck was found between 31 to 35 years and in the lumbar spine between 26-30 years. In these groups, the bone mineral density falls as age rises. When we compare our results to reference population from the LUNAR densitometer database and to our same study group, there is an overestimation of the prevalence of OP and osteopenia on the lumbar spine and osteopenia on the femoral neck. We found a prevalence of overweight and obesity higher to reported at the Mexican National Survey of Nutrition.
墨西哥人群中骨质疏松症(OP)的患病率尚不清楚。这种疾病是OP导致骨折的一个危险因素,骨折会导致残疾、生活质量下降和死亡率上升。
使用中心骨密度测量法(双能X线吸收法-DXA)确定一组来自墨西哥城的女性卫生工作者中OP和骨质减少的患病率;比较LUNAR DPX L设备的西班牙裔参考数据库与研究人群;确定达到峰值骨量的年龄,并探讨一些已知的骨质疏松症因素与骨量之间的关系。
在这项前瞻性横断面观察研究中,选取了588名年龄超过18岁的健康女性,她们处于不同阶段,使用LUNA DPX L设备进行了髋部和脊柱骨密度测量(DXA)。为了确定骨质疏松症和骨质减少的患病率,我们采用了世界卫生组织骨质疏松症专家委员会的标准。
我们研究人群的平均年龄为42.3岁±9.6(20-65岁);体重66公斤±12.1(41-139公斤),身高153.9厘米±5.7(138-177厘米)。腰椎骨质疏松症的患病率为13.5%(95%置信区间:10.5-16),骨质减少为27.7%(95%置信区间:24-31)。在股骨颈,骨质疏松症的患病率为2%(95%置信区间:1.0-3),骨质减少为26.1%(95%置信区间:22-29)。股骨颈的峰值骨量在31至35岁之间,腰椎在26-30岁之间。在这些组中,骨矿物质密度随年龄增长而下降。当我们将我们的结果与LUNAR骨密度仪数据库的参考人群以及我们相同的研究组进行比较时,腰椎OP和骨质减少以及股骨颈骨质减少的患病率被高估。我们发现超重和肥胖的患病率高于墨西哥全国营养调查的报告。