[通过骨密度测定法评估绝经后女性骨质疏松症和骨质减少症的患病率]

[Prevalence of osteopenia and osteoporosis assessed by densitometry in postmenopausal women].

作者信息

Guzmán Ibarra Ma, Ablanedo Aguirre Judith, Armijo Delgadillo Ricardo, García Ruíz Esparza Miriam

出版信息

Ginecol Obstet Mex. 2003 May;71:225-32.

Abstract

OBJECTIVE

Our goal was to know the osteopenia and osteoporosis prevalence, determined by densitometry using dual energy X-ray absorptiometry (DXA) to measure the bone mineral density (BMD) in postmenopausal women.

SUBJECTS AND METHODS

A total the 202 postmenopausal women aged 37 at 74 years old was studied, at the Gynecologist and Obstetrics Hospital No. 3 Medical Center "La Raza" from the IMSS, initiated in December 2001 to June 2002. The measurement BMD using DXA with a LUNAR device and according the WHO criteria, we have calculated the prevalence of osteopenia and osteoporosis in normal postmenopausal women at the lumbar spine (LS) and/or femoral neck (FN).

RESULTS

The osteopenia prevalence in LS was: 18.2% in the group aged 45-49 years old, 47.1% in the group aged 50-54, 43.7% in the group aged 55-59, 63.6 in the group aged 60-64, 53% in the group aged 65-69, and 30% in the group aged 70-74. The overall osteopenia prevalence in LS was 43.5%, confidence interval (CI) 95% from 43.08 to 44.03%. The osteoporosis of LS was 17.1% in the group aged 50-54 years old; 21.8 in the group aged 55-59; 22.7 in the group aged 60-64; 35.29% in the group aged 65-69; and 30% in the group aged 70-74. The overall osteoporosis prevalence in the LS was 19.8% (CI) 95% from 14.3 to 25.2%. The osteopenia prevalence in FN was. 19% in the group aged 45-49 years old; 40% in the group aged 50-54; 49% in the group aged 55-59; 54% in the group aged 60-64; 76% in the group aged 65-69 and 60% in the group aged 70-74. The overall osteopenia prevalence of FN was the 48% CI 95% from 40.65-54.59%. The osteoporosis prevalence in FN: 2.38% in the group aged 45-49 years old; 7.14 in the group aged 50-54; 5.45% in the group aged 55-59; 13.6% in the group aged 60-64; 5.8 in the group aged 65-69, and 20% in the group aged 70-74. The overall osteoporosis prevalence in FN was 7.4% IC 95% from 3.6-10.68%.

CONCLUSIONS

The osteoporosis prevalence in this group is less than between American women (15%), and early detection is possible between women with BMD low, in the postmenopausal women with high risk factors and primary treatment need to be established and implemented.

摘要

目的

我们的目标是通过使用双能X线吸收法（DXA）测量骨矿物质密度（BMD）的密度测定法，了解绝经后女性骨质疏松症和骨质减少症的患病率。

对象与方法

对墨西哥社会保险协会（IMSS）第3医疗中心“拉扎”妇产科医院200名年龄在37至74岁之间的绝经后女性进行了研究，研究于2001年12月至2002年6月开展。使用LUNAR设备通过DXA测量BMD，并根据世界卫生组织标准，我们计算了正常绝经后女性腰椎（LS）和/或股骨颈（FN）处骨质减少症和骨质疏松症的患病率。

结果

LS处骨质减少症的患病率为：45至49岁组为18.2%，50至54岁组为47.1%，55至59岁组为43.7%，60至64岁组为63.6%，65至69岁组为53%，70至74岁组为30%。LS处总体骨质减少症患病率为43.5%，95%置信区间（CI）为43.08至44.03%。LS处骨质疏松症患病率在50至54岁组为17.1%；55至59岁组为21.8%；60至64岁组为22.7%；65至69岁组为35.29%；70至74岁组为30%。LS处总体骨质疏松症患病率为19.8%（95%CI）为14.3至25.2%。FN处骨质减少症患病率为：45至49岁组为19%；50至54岁组为40%；55至59岁组为49%；60至64岁组为54%；65至69岁组为76%；70至74岁组为60%。FN处总体骨质减少症患病率为48%（95%CI）为40.65至54.59%。FN处骨质疏松症患病率为：45至49岁组为2.38%；50至54岁组为7.14%；55至59岁组为5.45%；60至64岁组为13.6%；65至69岁组为5.8%；70至74岁组为20%。FN处总体骨质疏松症患病率为7.4%（95%IC）为3.6至10.68%。