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[生化标志物在子宫内膜异位症诊断中的应用]

[The use of biochemical markers in diagnosis of endometriosis].

作者信息

Nalbanski A, Kiurkchiev D

出版信息

Akush Ginekol (Sofiia). 2008;47(4):19-22.

Abstract

The aim of this study was to evaluate Ca 125 II, C-reactive protein (CRP) and serum amyloid A (SAA) and anticardiolipin antibody (aCL) concentrations for the diagnosis of pelvic endometriosis. The study population consisted of 15 women without endometriosis, as confirmed by laparoscopy (group A), and 35 patients with pelvic endometriosis. All of them were diagnosed by laparoscopy or laparotomy. Group B patients were divided into those at stages I and II of the disease (B I/II) and those at stages III and IV (B III/IV). Blood samples were obtained twice during the menstrual cycle: on day 1-3 of the cycle and on day 8-10 of the cycle. Our results claim that the measurement of these molecules may therefore provide a valuable tool in the diagnosis and management of endometriosis.

摘要

本研究的目的是评估癌抗原125 II(Ca 125 II)、C反应蛋白(CRP)、血清淀粉样蛋白A(SAA)和抗心磷脂抗体(aCL)的浓度,以用于盆腔子宫内膜异位症的诊断。研究对象包括15名经腹腔镜检查确诊无子宫内膜异位症的女性(A组)和35名盆腔子宫内膜异位症患者。所有患者均通过腹腔镜检查或剖腹手术确诊。B组患者分为疾病I期和II期(B I/II)以及III期和IV期(B III/IV)。在月经周期中采集两次血样:在周期的第1 - 3天和第8 - 10天。我们的结果表明,因此这些分子的检测可能为子宫内膜异位症的诊断和管理提供有价值的工具。

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