Yalçindag F Nilüfer, Incel Osman, Ozdemir Ozden
Ankara University Faculty of Medicine, Ophthalmology Department, Ankara, Turkey.
Ann Ophthalmol (Skokie). 2008 Fall-Winter;40(3-4):152-6.
We evaluated the efficacy and safety of tacrolimus in prevention of allograft rejection in high-risk allo-limbal grafts. Six eyes of six patients with severe limbal stem cell deficiency were included. All patients were started 0.1 mg x kg 1 x day(-1) tacrolimus orally 3 days before the surgery. Limbal allo-graft transplantation for ocular surface reconstruction had a successful outcome with using systemic tacrolimus for immunosuppression.
我们评估了他克莫司在预防高风险同种异体角膜缘移植排斥反应中的疗效和安全性。纳入了6例严重角膜缘干细胞缺乏患者的6只眼。所有患者在手术前3天开始口服他克莫司，剂量为0.1mg·kg-1·d-1。使用全身性他克莫司进行免疫抑制，角膜缘同种异体移植用于眼表重建取得了成功的结果。
