Chaowalit Nithima, Jakrapanichakul Decho, Udol Kamol, Kitrattana Bussakorn
Division of Cardiology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
J Med Assoc Thai. 2007 Nov;90 Suppl 2:33-40.
No previous report of dobutamine stress echocardiography in the Thai population has been available. The present study seeks to document the protocol, indications, results and safety of dobutamine stress echocardiography performed at Siriraj Hospital.
The authors studied 421 [mean age 67.7 +/- 11.0 years, 179 (43%) men] consecutive Thai patients undergoing dobutamine stress echocardiography at Siriraj Hospital. The protocol, indications and echocardiographic analysis were described. Clinical characteristics, hemodymanics, results and adverse effects were recorded at the time of dobutamine stress echocardiography.
Dobutamine stress echocardiography was performed for preoperative assessment before non-cardiac surgery in 212 patients (50%), for the diagnosis of suspected Coronary Artery Disease (CAD) in 179 patients (43%), for risk stratification of CAD in 24 patients (6%), and for other reasons in six patients (1%). The results were normal and positive for inducible ischemia in 276 (66%) and 80 (19%) patients, respectively. Limiting side effects were observed in 3%. No death, myocardial infarction or life-threatening arrhythmias occurred. Transient stress-associated tachyarrhythmias, such as atrialfibrillation, nonsustained ventricular tachycardia or supraventricular tachycardia, occurred in 3.5% of patients.
Dobutamine stress echocardiography was considered a safe and tolerable technique for the evaluation of CAD in Thai population.
此前尚无关于泰国人群多巴酚丁胺负荷超声心动图的报道。本研究旨在记录诗里拉吉医院进行多巴酚丁胺负荷超声心动图的方案、适应证、结果及安全性。
作者研究了诗里拉吉医院连续接受多巴酚丁胺负荷超声心动图检查的421例泰国患者[平均年龄67.7±11.0岁，179例（43%）为男性]。描述了方案、适应证及超声心动图分析方法。在多巴酚丁胺负荷超声心动图检查时记录临床特征、血流动力学、结果及不良反应。
212例患者（50%）因非心脏手术前评估行多巴酚丁胺负荷超声心动图检查，179例患者（43%）用于诊断疑似冠心病（CAD），24例患者（6%）用于CAD危险分层，6例患者（1%）因其他原因进行该项检查。结果分别显示276例患者（66%）正常、80例患者（19%）诱发缺血阳性。观察到3%的患者出现了限制性副作用。未发生死亡、心肌梗死或危及生命的心律失常。3.5%的患者出现短暂的应激相关快速性心律失常，如房颤、非持续性室性心动过速或室上性心动过速。
多巴酚丁胺负荷超声心动图被认为是评估泰国人群CAD的一种安全且可耐受的技术。
