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使用最小体外循环系统的微创主动脉瓣置换术。

Minimal access aortic valve replacement using a minimal extracorporeal circulatory system.

作者信息

Yilmaz Alaadin, Rehman Atiq, Sonker Uday, Kloppenburg Geoffrey T L

机构信息

Department of Cardiothoracic Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands.

出版信息

Ann Thorac Surg. 2009 Mar;87(3):720-5. doi: 10.1016/j.athoracsur.2008.12.016.

Abstract

BACKGROUND

Minimal access aortic valve replacement (mAVR) has been demonstrated to be beneficial over standard median sternotomy. Similarly, minimal extracorporeal circulation (MECC) has been shown to have less deleterious effects than conventional cardiopulmonary bypass. We report a previously undescribed technique for AVR in combination with MECC by minimal access.

METHODS

We prospectively collected data including one-month postoperative follow-up of the first 50 patients who underwent mAVR utilizing MECC. A temporary Cordis Ventricor (Cordis Corp, Miami, FL) ventricular pacemaker and external defibrillation pads were placed at induction. A J-shaped partial upper sternotomy ending in the third intercostal space was performed. Cannulation was performed in the groin using the Seldinger technique. A vent was introduced directly in the pulmonary artery. Warm blood cardioplegia and carbon dioxide field flooding were used.

RESULTS

Fifty consecutive patients (24 male) with a mean age of 68 (range, 34 to 89) were operated between May and December 2007. Operating time was 147 +/- 20 minutes, cross-clamp time was 64 +/- 10 minutes, and perfusion time was 84 +/- 17 minutes. There were no conversions to median sternotomy. Only one peroperative blood transfusion was required and postoperative blood loss was 372 +/- 170 cc. Intensive care unit stay was uneventful (average stay 2 days, range 1 to 8). One patient required a permanent pacemaker and other complications included pneumothorax, superficial wound infection, a late transient postoperative neurologic deficit, and excessive postoperative blood loss requiring mediastinal reexploration. Renal failure and major cerebral accidents did not occur. There was a 100% survival at one-month follow-up.

CONCLUSION

We have shown that minimal access aortic valve replacement using minimal extracorporeal circulation is feasible and provides excellent clinical and cosmetic results.

摘要

背景

已证明微创主动脉瓣置换术(mAVR)比标准正中开胸手术更具优势。同样,与传统体外循环相比,微创体外循环(MECC)已显示出危害较小。我们报告了一种通过微创方式将AVR与MECC相结合的此前未描述的技术。

方法

我们前瞻性收集了首批50例行mAVR并采用MECC患者术后1个月随访的数据。诱导时放置临时Cordis Ventricor(Cordis公司,迈阿密,佛罗里达州)心室起搏器和体外除颤电极片。进行了一个在第三肋间间隙结束的J形部分上胸骨切开术。采用Seldinger技术在腹股沟进行插管。直接在肺动脉中插入一根引流管。使用温血心脏停搏液和二氧化碳术野灌注。

结果

2007年5月至12月期间,连续对50例患者(24例男性)进行了手术,平均年龄68岁(范围34至89岁)。手术时间为147±20分钟,主动脉阻断时间为64±10分钟,灌注时间为84±17分钟。无一例转为正中开胸手术。仅需术中输血1次,术后失血量为372±170毫升。重症监护病房停留期间情况平稳(平均停留2天,范围1至8天)。1例患者需要植入永久性起搏器,其他并发症包括气胸、浅表伤口感染、术后晚期短暂性神经功能缺损以及术后失血过多需要再次开胸探查纵隔。未发生肾衰竭和重大脑部意外。1个月随访时生存率为100%。

结论

我们已证明,使用微创体外循环进行微创主动脉瓣置换术是可行的,并能提供出色的临床和美容效果。

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