Kohli Simi, Gao Min, Lear Scott A
School of Kinesiology, Simon Fraser University, Burnaby, BC V6Z1Y6, Canada.
Appl Physiol Nutr Metab. 2009 Feb;34(1):40-8. doi: 10.1139/H08-128.
Previously determined predictive equations for body fat mass (BFM) are primarily derived from populations of European origin, which may not be appropriate for all ethnic groups. The objective of this study was to develop an improved predictive equation for BFM specific to South Asians and derived from common anthropometric measurements that include measures of central adiposity. A total of 208 apparently healthy South Asian men and women, aged 30-65 years, were recruited. Anthropometric measurements and BFM by dual energy X-ray absorbitometry (DEXA) were obtained. Sex-specific equations predicting BFM were developed using regression models on a reference subset (68 men, 70 women) and tested on a validation group. New predictive equations (BFMNEW) were tested for agreement with Durin and Wormersley and Siri equations and with the reference method, DEXA. The best predictive sex-specific equation involved a combination of skinfolds, waist circumference, hip circumference, humerus breadth, height, mass, and age. Models significantly correlated with BFM determined by DEXA (r = 0.946 for men; r = 0.974 for women; p < 0.001). The estimates of BFM from reference and validation groups had excellent correlations and displayed excellent agreement to DEXA measures. We demonstrated new predictive equations for BFM that are specific to South Asians and incorporate measures of central adiposity. This may help resolve issues surrounding inaccurate determination of adiposity in South Asians, and consequently provide better estimations of disease risk.
先前确定的身体脂肪量(BFM)预测方程主要源自欧洲裔人群,可能并不适用于所有种族群体。本研究的目的是针对南亚人开发一种改进的BFM预测方程,该方程源自包括中心性肥胖测量在内的常见人体测量指标。总共招募了208名年龄在30至65岁之间、表面健康的南亚男性和女性。获取了人体测量指标以及通过双能X线吸收法(DEXA)测得的BFM。使用回归模型在一个参考子集(68名男性,70名女性)上开发了预测BFM的性别特异性方程,并在一个验证组上进行了测试。对新的预测方程(BFMNEW)与杜林和沃默斯利方程以及西里方程和参考方法DEXA进行了一致性测试。最佳的预测性别特异性方程涉及皮褶厚度、腰围、臀围、肱骨宽度、身高、体重和年龄的组合。模型与通过DEXA测定的BFM显著相关(男性r = 0.946;女性r = 0.974;p < 0.001)。参考组和验证组的BFM估计值具有极好的相关性,并且与DEXA测量结果显示出极好的一致性。我们展示了针对南亚人的新的BFM预测方程,该方程纳入了中心性肥胖的测量指标。这可能有助于解决围绕南亚人肥胖程度测定不准确的问题,从而更好地估计疾病风险。