Balázs M, Vadász G, Koncz I, Simon E
Fövárosi Tanács János Kórháza Kórbonctani Osztály.
Orv Hetil. 1991 Sep 29;132(39):2143-6.
15 patients with congestive gastropathy were reported including clinical and pathological characteristics of the disease. Every patient had alcoholic liver cirrhosis and portal hypertension. 6 patient's stomach was resected while in 2 further cases the disease was found at autopsy. In additional 7 cases the characteristic microvascular changes were observed in endoscopic biopsy specimens from the gastric mucosa. The authors presume that this disease has an acute and a chronic stage. In the acute stage dilated capillaries are present under the surface, not related to the inflammation of gastric mucosa. This phenomenon was described in the literature. In the chronic stage there are dilated and tortuous vessels in the submucosal layer surrounded by collagenous connective tissue. The authors suppose that the thick and fibrotic submucosal layer causes microcirculatory disturbances in the gastric mucosa. The impaired microcirculation may cause extensive ulcers with profuse and sometimes lethal bleeding.
报告了15例充血性胃病患者，包括该疾病的临床和病理特征。每位患者均患有酒精性肝硬化和门静脉高压症。6例患者的胃被切除，另有2例在尸检时发现该病。在另外7例中，在胃黏膜的内镜活检标本中观察到特征性微血管变化。作者推测该疾病有急性期和慢性期。在急性期，表面下存在扩张的毛细血管，与胃黏膜炎症无关。这种现象在文献中已有描述。在慢性期，黏膜下层有扩张和迂曲的血管，周围有胶原结缔组织。作者认为增厚和纤维化的黏膜下层会导致胃黏膜微循环障碍。微循环受损可能导致广泛溃疡并伴有大量出血，有时甚至致命。
