de Ronde Willem
VU University Medical Center, Department of Endocrinology, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Expert Opin Biol Ther. 2009 Feb;9(2):249-53. doi: 10.1517/14712590802653593.
Testosterone supplementation is a standard treatment for young men with hypogonadism and has also been advocated as a treatment for symptomatic older men with low testosterone levels. Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels.
To review the literature concerning therapeutic efficacy and potential limitations of testosterone gels.
The FDA medical reviews and the computerised database PubMed were searched for clinical trials studying currently approved testosterone gels.
RESULTS/CONCLUSIONS: Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
睾酮补充疗法是年轻性腺功能减退男性的标准治疗方法，也被提倡用于治疗有症状的低睾酮水平老年男性。有多种睾酮替代方式可供选择，包括胶囊、贴片、注射剂、口腔含片和凝胶。
综述有关睾酮凝胶治疗效果及潜在局限性的文献。
检索美国食品药品监督管理局（FDA）的医学审评资料以及计算机数据库PubMed，查找研究目前已获批睾酮凝胶的临床试验。
结果/结论：睾酮凝胶已被证明对现有的睾酮治疗方式有重要贡献，兼具治疗效果、便利性和安全性。
