Keung Charlotte Y, Smith Katherine R, Savoia Helen F, Davidson Andrew J
Department of Anaesthesia, Royal Children's Hospital, Melbourne, Australia.
Paediatr Anaesth. 2009 Apr;19(4):320-8. doi: 10.1111/j.1460-9592.2009.02939.x. Epub 2009 Feb 19.
Patients undergoing surgery are an important user of red blood cells (RBC). Increasingly, medical staff and patients wish to know the likelihood of RBC transfusion for appropriate resource allocation and to inform preoperative discussions regarding risk. Although some adult data are available, little is known about RBC use in children.
The aim of this study was to describe RBC use in the perioperative period in a large pediatric hospital.
Over a 2-year period the hospital operating theatre database and trauma registry was merged with the blood bank database to identify episodes where RBC units were transfused in association with anesthesia. Incidence of transfusion of RBC units associated with particular procedures was then calculated.
A total of 21 441 patients underwent 32 511 anesthetics from January 1, 2006 to December 31, 2007, and 9838 units of RBC were released from the hospital blood bank of which 4070 (41%) were transfused in the perioperative period. Cardiac surgery was the greatest user of RBC units (2359 units). Acute major trauma accounted for only 159 units. Overall 6.3% of anesthetics were associated with a RBC transfusion. The procedures with the greatest frequency of RBC transfusion were cardiac surgery on bypass (79%), cardiac off bypass (55%), liver transplant (87%) and cranioplasty (61%).
In a tertiary pediatric hospital surgery accounts for a substantial proportion of total RBC use, with particular procedures accounting for the majority of transfusions.
接受手术的患者是红细胞(RBC)的重要使用者。医护人员和患者越来越希望了解红细胞输血的可能性,以便进行适当的资源分配,并为术前关于风险的讨论提供信息。虽然有一些成人数据,但关于儿童红细胞使用情况的了解却很少。
本研究的目的是描述一家大型儿科医院围手术期红细胞的使用情况。
在两年时间里,将医院手术室数据库和创伤登记处与血库数据库合并,以确定与麻醉相关的红细胞单位输血事件。然后计算与特定手术相关的红细胞单位输血发生率。
2006年1月1日至2007年12月31日,共有21441例患者接受了32511次麻醉,医院血库发放了9838单位的红细胞,其中4070单位(41%)在围手术期进行了输血。心脏手术是红细胞单位的最大使用者(2359单位)。急性重大创伤仅占159单位。总体而言,6.3%的麻醉与红细胞输血有关。红细胞输血频率最高的手术是体外循环心脏手术(79%)、非体外循环心脏手术(55%)、肝移植(87%)和颅骨成形术(61%)。
在一家三级儿科医院,手术占红细胞总使用量的很大一部分,特定手术占输血总数的大部分。