Department of Pathology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Transfusion. 2010 Apr;50(4):861-7. doi: 10.1111/j.1537-2995.2009.02524.x. Epub 2009 Dec 9.
Data-driven practices in preoperative red blood cell (RBC) preparation for pediatric surgical procedures are not well established. Adaptation of established adult preparation guidance methods to pediatric populations may improve perioperative RBC utilization.
A retrospective audit of preoperative RBC preparation volumes (Vp) and intraoperative RBC transfusion volumes (Vt) for pediatric surgical procedures was undertaken at a large children's hospital from January to June 2006. RBC preparation-to-transfusion volume (mL/kg) ratios (P:T) were calculated for all surgeries, subspecialties, and select procedures. P:T equals Vp divided by Vt. Resulting P:Ts were compared to a target P:T of 2:1. A model for maximum procedure-specific Vp (Vp-max) defined Vp-max as the RBC transfusion volume able to meet the needs of 80% of patients undergoing an individual surgical procedure. Vp-max values were applied to the study data set to predict the impact on P:Ts and Vp.
RBCs were prepared for 332 surgical procedures and transfused during 113 procedures. P:T was 3.5:1 for total surgical procedures (subspecialty range, 2.7:1-46:0), exceeding the 2:1 target. Vp-max modeling for spinal fusion, craniotomy for neoplasia, craniotomy for seizure, and craniosynostectomy yielded P:T ratios of 1.5:1, 1.5:1, 1.7:1, and 1.0:1, respectively, predicting a 30% decrease in Vp for these four surgical procedures.
P:Ts for pediatric surgical procedures at this institution indicate potentially excessive preoperative RBC preparations. Determination of data-driven procedure-specific Vp may increase the efficiency of preoperative RBC preparation practices.
小儿外科手术中术前红细胞(RBC)准备的数据驱动实践尚未得到很好的确立。将既定的成人准备指导方法应用于儿科人群可能会改善围手术期 RBC 的利用。
对 2006 年 1 月至 6 月期间一家大型儿童医院的小儿外科手术术前 RBC 准备量(Vp)和术中 RBC 输血量(Vt)进行了回顾性审计。所有手术、亚专科和特定手术均计算 RBC 准备与输血量(mL/kg)比(P:T)。P:T 等于 Vp 除以 Vt。所得 P:T 与 2:1 的目标 P:T 进行比较。一个特定手术最大体积(Vp-max)的模型定义为 Vp-max 为满足个别手术 80%患者需求的 RBC 输血体积。Vp-max 值应用于研究数据集以预测对 P:T 和 Vp 的影响。
共准备了 332 例手术用 RBC,并在 113 例手术中进行了输血。总手术(亚专科范围 2.7:1-46:0)的 P:T 为 3.5:1,超过 2:1 的目标。脊柱融合术、肿瘤性开颅术、癫痫性开颅术和颅缝早闭术的 Vp-max 建模分别产生 1.5:1、1.5:1、1.7:1 和 1.0:1 的 P:T 比值,预测这四个手术的 Vp 将减少 30%。
该机构小儿外科手术的 P:T 表明术前 RBC 准备可能过度。确定数据驱动的特定手术的 Vp 可能会提高术前 RBC 准备实践的效率。