Li Hong, Ding Guohui, Xie Lu, Li Yixue
Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China.
Bioinformatics. 2009 Apr 15;25(8):1094-5. doi: 10.1093/bioinformatics/btp100. Epub 2009 Feb 23.
PAnnBuilder is an R package to automatically assemble protein annotation information from public resources to provide uniform annotation data for large-scale proteomic studies. Sixteen public databases have been parsed and 54 annotation packages have been constructed based on R environment or SQLite database. These ready-to-use packages cover most frequently needed protein annotation for three model species including human, mouse and rat. Several extended applications such as annotation based on protein sequence similarity are also provided. Sophisticated users can develop their own packages using PAnnBuilder. PAnnBuilder may become an important tool for proteomic research.
PAnnBuilder是一个R软件包，用于从公共资源中自动组装蛋白质注释信息，为大规模蛋白质组学研究提供统一的注释数据。它解析了16个公共数据库，并基于R环境或SQLite数据库构建了54个注释包。这些即用型包涵盖了人类、小鼠和大鼠这三种模式物种最常需要的蛋白质注释。还提供了一些扩展应用，如基于蛋白质序列相似性的注释。经验丰富的用户可以使用PAnnBuilder开发自己的包。PAnnBuilder可能会成为蛋白质组学研究的重要工具。
