Kulinskiĭ V I, Kovalevskiĭ A N
Biull Eksp Biol Med. 1977 Feb;83(2):177-80.
Isopropylnoradrenaline (ISO), 3',5'-AMP and dibutyryl-3',5'-AMP decreased the oxygen tension (pO2) in the liver and the spleen and increased the body oxygen consumption (VO2). Time dynamics of these two effects was closely correlated for ISO and 3',5'-AMP. An increase of heat output was not accompanied by any significant changes in the respiration coefficient. Pempidine and dihydroergotamine failed to prevent 3',5'-AMP effects; inderal somewhat decreased these effects. Apparently, the catecholamine influence upon pO2 was a result of the VO2 increase through 3'5'-AMP effects are largely direct, but they include the in vivo and beta-receptor component; 2',3'-AMP decreased pO2 and VO2.
异丙去甲肾上腺素（ISO）、3',5'-腺苷酸（3',5'-AMP）和二丁酰-3',5'-腺苷酸降低了肝脏和脾脏中的氧分压（pO2），并增加了机体耗氧量（VO2）。ISO和3',5'-AMP这两种效应的时间动态密切相关。产热增加并未伴随着呼吸系数的任何显著变化。潘必定和双氢麦角胺未能阻止3',5'-AMP的效应；心得安在一定程度上减弱了这些效应。显然，儿茶酚胺对pO2的影响是VO2增加的结果，3',5'-AMP的效应在很大程度上是直接的，但它们包括体内和β受体成分；2',3'-AMP降低了pO2和VO2。
