Taranukhin Andrey G, Taranukhina Elena Y, Djatchkova Irina M, Saransaari Pirjo, Pelto-Huikko Markku, Oja Simo S
Brain Research Center, University of Tampere Medical School, Finland.
Adv Exp Med Biol. 2009;643:159-67. doi: 10.1007/978-0-387-75681-3_16.
Acute ethanol administration causes extensive apoptosis throughout the nervous system. We studied the protective effect of taurine on alcohol-induced apoptosis in the cerebellum of developing mice. Taurine rescued a part of immature neurons by markedly reducing caspase-3 immunoreactivity and the number of TUNEL-positive cells in most cerebellar lobules.
急性给予乙醇会导致整个神经系统广泛的细胞凋亡。我们研究了牛磺酸对发育中小鼠小脑酒精诱导的细胞凋亡的保护作用。牛磺酸通过显著降低大多数小脑小叶中caspase-3免疫反应性和TUNEL阳性细胞数量，挽救了一部分未成熟神经元。
