Mazeika P K, Nihoyannopoulos P, Nadazdin A, Oakley C M
Department of Medicine, Hammersmith Hospital, Royal Postgraduate Medical School, London, UK.
Postgrad Med J. 1991;67 Suppl 1:S21-35.
This article deals with the application of pharmacological stress echocardiography, a relatively new and evolving technique, to the diagnosis and assessment of patients with coronary artery disease. The value of echocardiography in ischaemic heart disease is initially outlined, followed by a brief review of the exercise two-dimensional echocardiography and exercise echo-Doppler literature. Dipyridamole, adenosine and dobutamine stress echocardiography are then examined, and the rationale and potential advantages of this approach explained. The findings of our own work using dipyridamole and dobutamine stress, combined with both two-dimensional echocardiography and Doppler, are then described. A review of the various methods of echocardiographic image analysis is then presented and the article concludes by suggesting directions for future work.
本文探讨了药物负荷超声心动图这一相对较新且不断发展的技术在冠状动脉疾病患者诊断和评估中的应用。文章首先概述了超声心动图在缺血性心脏病中的价值，接着简要回顾了运动二维超声心动图和运动回声多普勒的文献。然后研究了双嘧达莫、腺苷和多巴酚丁胺负荷超声心动图，并解释了这种方法的基本原理和潜在优势。随后描述了我们自己使用双嘧达莫和多巴酚丁胺负荷，结合二维超声心动图和多普勒的研究结果。接着介绍了超声心动图图像分析的各种方法，文章最后提出了未来工作的方向。
