May R P, Mayer A
Eur J Biochem. 1975 Apr 1;52(3):589-93. doi: 10.1111/j.1432-1033.1975.tb04030.x.
Flash-photolysis experiments were performed on solutions of carbonmonoxy hemoglobin (human Hb A) as function as pH. The fraction of fast reaction and the amount of photodissociation as produced by a given amount of light quanta has been analyzed in terms of the allosteric model of ligand binding by Monod, Wyman and Changeux. It is shown how the switch-over point of the allosteric transition from the T or R state is controlled by the protons, which act as allosteric effectors.
对碳氧血红蛋白（人血红蛋白A）溶液进行了闪光光解实验，该实验是作为pH的函数进行的。根据莫诺德、怀曼和尚热提出的配体结合别构模型，分析了快速反应的分数以及给定数量光量子产生的光解离量。结果表明，别构转变从T态或R态的转换点是如何由质子控制的，质子作为别构效应剂发挥作用。
