Kennedy P S, Lehane D E, Smith F E, Lane M
Cancer. 1977 May;39(5):1930-5. doi: 10.1002/1097-0142(197705)39:5<1930::aid-cncr2820390503>3.0.co;2-7.
Oral fluorouracil was administered weekly to 12 consecutive patients with unresectable hepatoma. Six patients showed an objective response with a significant increase in survival duration compared to nonresponders and to untreated patients. The clinical features of these cases are discussed, along with details of therapy, and possible reasons for the encouraging results noted with this treatment regimen.
对12例连续的无法切除的肝癌患者每周给予口服氟尿嘧啶。与无反应者和未治疗的患者相比,6例患者出现客观反应,生存时间显著延长。本文讨论了这些病例的临床特征、治疗细节以及该治疗方案取得令人鼓舞结果的可能原因。