Gitau Mark M, Arora Navanshu
Division of Hematology and Oncology, University of Missouri-Kansas City School of Medicine, USA.
Mo Med. 2009 Jan-Feb;106(1):50-4.
Heparin-Induced Thrombocytopenia (HIT) is a well recognized, potentially life-threatening, complication of heparin therapy. It is associated with an increased risk of thrombosis which can be sometimes fatal. Making the diagnosis of HIT can be quite challenging for the clinician as it requires recognition of the tell-tale clinical presentation as well as positive confirmation with appropriate laboratory diagnostic tests. This paper reviews the pathophysiology, recognition, treatment and prevention of HIT for the clinical physician.
肝素诱导的血小板减少症（HIT）是肝素治疗中一种公认的、可能危及生命的并发症。它与血栓形成风险增加相关，血栓形成有时可能是致命的。对临床医生而言，诊断HIT颇具挑战性，因为这需要识别典型的临床表现，并通过适当的实验室诊断测试进行阳性确认。本文为临床医生综述了HIT的病理生理学、识别、治疗及预防。
