99mTc 红细胞单光子发射计算机断层扫描及平面闪烁扫描在肝血管瘤诊断中的应用

99mTc-red blood cells SPECT and planar scintigraphy in the diagnosis of hepatic hemangiomas.

作者信息

Artiko M V, Sobić-Saranović P D, Perisić-Savić S M, Stojković V M, Radoman B I, Knezević S J, Petrović S N, Obradović B V, Milović V

机构信息

Institute for Nuclear Medicine, Clinical Center of Serbia.

出版信息

Acta Chir Iugosl. 2008;55(4):23-6. doi: 10.2298/aci0804023a.

DOI:10.2298/aci0804023a

PMID:19245136

Abstract

The aim of the study is the assessment of the value of SPECT (single photon emission computerized tomography) using 99mTc-labeled red blood cells in the detection of liver hemangioma, in comparison to planar imaging. With planar red blood cell scintigraphy, sensitivity of the method was 76%, specificity 98%, positive predictive value 98% and negative predictive value 79%. With SPECT, sensitivity of the method was 95%, specificity 98%, positive predictive value 98% and negative predictive value 94%. The smallest lesion detected by planar red blood cell scintigraphy was 1.2 cm, and with SPECT red blood cell scintigraphy 0.8 cm. The use of 99mTc-labeled red blood cells SPECT improved the sensitivity much more in smaller lesions (0.8 to 2 cm), than in bigger ones (2-5 cm). SPECT with radiolabeled red blood cells significantlyy improves the results of scintigraphic findings, especially in the small lesions.

摘要

本研究的目的是评估使用99mTc标记的红细胞的单光子发射计算机断层扫描（SPECT）在检测肝血管瘤方面相对于平面成像的价值。对于平面红细胞闪烁扫描，该方法的灵敏度为76%，特异性为98%，阳性预测值为98%，阴性预测值为79%。对于SPECT，该方法的灵敏度为95%，特异性为98%，阳性预测值为98%，阴性预测值为94%。平面红细胞闪烁扫描检测到的最小病变为1.2厘米，而SPECT红细胞闪烁扫描为0.8厘米。使用99mTc标记的红细胞SPECT在较小病变（0.8至2厘米）中比在较大病变（2 - 5厘米）中更能提高灵敏度。放射性标记红细胞的SPECT显著改善了闪烁扫描结果，尤其是在小病变中。