de Leon Jean M, Barnes Sunni, Nagel Melody, Fudge Michelle, Lucius Adora, Garcia Betty
Baylor Specialty Hospital Wound Care and Outpatient Wound Care Center, Dallas, Texas, USA.
Adv Skin Wound Care. 2009 Mar;22(3):122-7. doi: 10.1097/01.ASW.0000305452.79434.d9.
To evaluate the cost-effectiveness of negative pressure wound therapy (NPWT) using reticulated open-cell foam (NPWT/ROCF) as delivered by a Vacuum-Assisted Closure* (KCI Licensing, Inc, San Antonio, Texas) in patients with complex wounds in a long-term acute care (LTAC) setting. These patients are routinely discharged to LTAC hospitals with the goal of accelerating wound healing and timely transfer to a lower acuity care setting and are usually affected with serious comorbidities and deep, complex wounds with exposed anatomical structures, which require extended care (stay > 25 days).
A retrospective chart review was conducted to determine the average daily wound volume reduction, average daily wound area reduction, and average cost per cubic centimeter of wound volume reduction for patients treated with NPWT/ROCF as compared with topical advanced moist healing strategies (non-NPWT).
All patients received treatment in an LTAC hospital.
Patients admitted from November 2001 to August 2004 were identified using a computerized hospital database. The inclusion criteria were postsurgical patients of at least 18 years of age, with a single acute wound.
Patients were treated with either NPWT/ROCF or advanced moist wound-healing therapies (non-NPWTs).
Data collected included age, sex, wound measurements, Bates-Jensen Wound Assessment Tool severity score, procedures performed, wound care products and devices used, wound-healing outcomes, and costs associated with treatment.
Fifty-one patients met the inclusion criteria: 36 were identified as NPWT/ROCF and 15 as non-NPWT. The NPWT/ROCF patients showed a statistically significantly higher average daily rate of volume reduction as compared with the advanced moist wound-healing group (5.02 +/- 13.36 vs 0.40 +/- 0.88 cm(3)/day; P = .046). The cost per cubic centimeter reduction was $11.90/cm(3) in the NPWT/ROCF group versus $30.92/cm in the moist wound-healing group.
Postsurgical LTAC patients who were treated by NPWT/ROCF had a more accelerated rate of wound closure, compared with patients treated with advanced moist wound-healing therapy. These results suggest that, for this patient group, NPWT/ROCF may be more clinically effective in reducing wound volume, compared with advanced moist wound healing. Furthermore, the lower cost per cubic centimeter volume reduction suggests that NPWT/ROCF produces a more favorable cost-effective solution. Therefore, it is important when developing a wound-healing strategy that cost decisions be based on overall cost and not individual product cost when using advanced technology as part of the overall treatment plan. This study serves as a basis for further work in cost-benefit analysis when considering evidence-based outcomes in wound care.
评估在长期急性护理(LTAC)环境中,使用网状开孔泡沫(NPWT/ROCF)的负压伤口治疗(NPWT),通过真空辅助闭合装置(KCI Licensing公司,得克萨斯州圣安东尼奥)对复杂伤口患者的成本效益。这些患者通常被送往LTAC医院,目的是加速伤口愈合并及时转至较低护理级别环境,且通常患有严重合并症以及伴有解剖结构暴露的深部复杂伤口,需要长期护理(住院时间>25天)。
进行一项回顾性病历审查,以确定接受NPWT/ROCF治疗的患者与局部高级湿性愈合策略(非NPWT)相比,每天伤口体积减少的平均值、每天伤口面积减少的平均值以及每立方厘米伤口体积减少的平均成本。
所有患者均在一家LTAC医院接受治疗。
使用医院计算机数据库确定2001年11月至2004年8月入院的患者。纳入标准为年龄至少18岁的术后患者,且有单个急性伤口。
患者接受NPWT/ROCF或高级湿性伤口愈合疗法(非NPWT)治疗。
收集的数据包括年龄、性别、伤口测量值、贝茨-詹森伤口评估工具严重程度评分、进行的手术、使用的伤口护理产品和设备、伤口愈合结果以及治疗相关成本。
51名患者符合纳入标准:36名被确定为NPWT/ROCF组,15名被确定为非NPWT组。与高级湿性伤口愈合组相比,NPWT/ROCF组患者每天体积减少率在统计学上显著更高(5.02±13.36 vs 0.40±0.88 cm³/天;P = 0.046)。NPWT/ROCF组每立方厘米减少的成本为11.90美元/cm³,而湿性伤口愈合组为30.92美元/cm³。
与接受高级湿性伤口愈合疗法治疗的患者相比,接受NPWT/ROCF治疗的术后LTAC患者伤口闭合速度更快。这些结果表明,对于该患者群体,与高级湿性伤口愈合相比,NPWT/ROCF在减少伤口体积方面可能更具临床效果。此外,每立方厘米体积减少成本较低表明NPWT/ROCF产生了更有利的成本效益解决方案。因此,在制定伤口愈合策略时,当将先进技术作为整体治疗计划的一部分时,成本决策应基于总成本而非单个产品成本,这一点很重要。本研究为在伤口护理中考虑循证结果时进行成本效益分析的进一步工作奠定了基础。