通过脱羧C-S交叉偶联反应合成芳基硫醚

Synthesis of aryl sulfides by decarboxylative C-S cross-couplings.

作者信息

Duan Zhongyu, Ranjit Sadananda, Zhang Pengfei, Liu Xiaogang

机构信息

Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.

出版信息

Chemistry. 2009;15(15):3666-9. doi: 10.1002/chem.200900133.

DOI:10.1002/chem.200900133

PMID:19248059

Abstract

Without the need for organohalide precursors, the convenient and general synthesis of aryl (or diaryl) sulfides can be achieved by using aryl carboxylic acids and thiols or disulfides for decarboxylative C-S cross-coupling catalyzed by a bimetallic system (see scheme).

摘要

无需有机卤化物前体，通过使用芳基羧酸和硫醇或二硫化物，在双金属体系催化下进行脱羧C-S交叉偶联反应，可便捷且通用地合成芳基（或二芳基）硫醚（见反应式）。