Charfi M R, Matran R, Regnard J, Richard M O, Champeau J, Dall'ava J, Lockhart A
Laboratoire d'Explorations Fonctionnelles Respiratoires, Hôpital, Cochin, Paris.
Rev Mal Respir. 1991;8(4):367-74.
Mouth pressure measured during maximal inspiratory or expiratory efforts depends on the force exerted by ventilatory muscles. Normal values and anthropometric factors accounting for maximal inspiratory and expiratory pressures (MIP, MEP) are not fully agreed upon to date. We measured MIP and MEP in 253 normal subjects (135 females and 118 males, age 15-59 years) using a digital transducer (163 Sibelmed). All subjects had normal forced vital capacity (FVC) and one second forced expiratory volume (FEV1). Sex, age, height and weight were recorded for all subjects and were entered as independent variables in computation of linear multiple regressions with MEP or MIP the dependent variables. MEP and MIP were greater in males than in females (p less than 0.01) with MIP lower than MEP in both sexes (p less than 0.01). In both males and females, FVC and FEV1 depend on age and height (p less than 0.01). In the entire group, we found a correlation of MIP in females and MEP in males with age (p less than 0.01) and of both MIP and MEP in females with weight (p less than 0.01). However, in subjects aged 20-59 years, there was no significant dependence of MIP and MEP on age, and when the weight of subjects was normal (n = 170), MIP and MEP were independent of weight. We conclude that in adults aged 20-59 years and with normal weight, maximal ventilatory pressures depend solely on sex. In this subgroup mean (+/- SD) values of MEP and MIP were 111 +/- 25 cmH2O and 79 +/- 19 cmH2O respectively in females and 192 +/- 42 cmH2O and 117 +/- 25 cmH2O in males.
在最大吸气或呼气努力过程中测量的口腔压力取决于呼吸肌施加的力量。迄今为止，关于最大吸气和呼气压力（MIP、MEP）的正常值以及影响这些值的人体测量因素尚未完全达成共识。我们使用数字传感器（163 Sibelmed）对253名正常受试者（135名女性和118名男性，年龄15 - 59岁）测量了MIP和MEP。所有受试者的用力肺活量（FVC）和一秒用力呼气量（FEV1）均正常。记录了所有受试者的性别、年龄、身高和体重，并将其作为自变量，以MEP或MIP作为因变量进行线性多元回归计算。男性的MEP和MIP高于女性（p < 0.01），且两性的MIP均低于MEP（p < 0.01）。在男性和女性中，FVC和FEV1均取决于年龄和身高（p < 0.01）。在整个组中，我们发现女性的MIP和男性的MEP与年龄相关（p < 0.01），女性的MIP和MEP均与体重相关（p < 0.01）。然而，在20 - 59岁的受试者中，MIP和MEP与年龄无显著相关性，当受试者体重正常时（n = 170），MIP和MEP与体重无关。我们得出结论，在20 - 59岁且体重正常的成年人中，最大通气压力仅取决于性别。在该亚组中，女性的MEP和MIP平均（±标准差）值分别为111 ± 25 cmH₂O和79 ± 19 cmH₂O，男性分别为192 ± 42 cmH₂O和117 ± 25 cmH₂O。
