New York University Fertility Center, New York University, New York, New York 10016, USA.
Fertil Steril. 2010 Apr;93(6):1837-43. doi: 10.1016/j.fertnstert.2008.12.137. Epub 2009 Feb 27.
To determine whether there is a difference in pregnancy outcomes, stratified by age, between women undergoing elective single blastocyst transfer (eSBT) versus those undergoing double blastocyst transfer (2BT).
Retrospective analysis.
University IVF center.
PATIENT(S): A total of 1,141 nondonor IVF cycles in women aged <40 years from January 2004-March 2007.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Eggs retrieved, embryos cryopreserved, implantation rates, clinical pregnancy rates (PR), live birth rates (LBR), spontaneous abortion rates (SAB).
RESULT(S): Pregnancy outcomes in 52 cycles of women <40 years of age who underwent eSBT were compared with 1,086 cycles of women who underwent 2BT in fresh IVF cycles from January 2004-March 2007. Overall, the eSBT was associated with a statistically significant 92% reduction in the twinning rate (from 25%-2%) while maintaining a high clinical PR (63% in the eSBT group vs. 61% in the 2BT group).
CONCLUSION(S): Women who are <40 years of age undergoing nondonor fresh IVF cycles can electively choose to transfer a single blastocyst for the purpose of significantly reducing their risk of multiples without compromising their PR.
确定在接受选择性单囊胚移植（eSBT）与接受双囊胚移植（2BT）的女性中，按年龄分层，妊娠结局是否存在差异。
回顾性分析。
大学试管婴儿中心。
2004 年 1 月至 2007 年 3 月期间年龄<40 岁的 1141 例非捐赠 IVF 周期的女性。
无。
取卵数、胚胎冷冻数、着床率、临床妊娠率（PR）、活产率（LBR）、自然流产率（SAB）。
比较了 2004 年 1 月至 2007 年 3 月期间年龄<40 岁的 52 例接受 eSBT 的女性与 1086 例接受新鲜 IVF 周期 2BT 的女性的妊娠结局。总体而言，eSBT 可使双胎率显著降低 92%（从 25%降至 2%），同时保持较高的临床 PR（eSBT 组为 63%，2BT 组为 61%）。
年龄<40 岁的非捐赠新鲜 IVF 周期的女性可选择进行单囊胚移植，以显著降低多胎妊娠的风险，而不会降低其妊娠率。
