Clarençon Frédéric, Blanc Raphaël, Gallas Sophie, Hosseini Hassan, Gaston André
Department of Neuroradiology, Faculty of Medicine, APHP-Henri Mondor Hospital, Créteil, France.
J Neurosurg. 2009 Jul;111(1):53-6. doi: 10.3171/2008.11.JNS081035.
Basilar artery occlusion is a dramatic clinical event with a high mortality rate if patients are treated by standard medical therapy, including anticoagulation agents. The use of intravenous tissue plasminogen activator or intraarterial thrombolysis recanalizes 30-53 and 64%, respectively, of patients with basilar stroke. Mechanical endovascular treatments allow tailored procedures with quicker results and higher recanalization rates. The authors describe a successful mechanical removal of an obstruction in an acute occlusion of the basilar artery tip involving both proximal segments of posterior cerebral arteries in a 20-year-old man. They used 2 Merci retriever devices at the same time, and performed bilateral proximal vertebral artery occlusion for temporary flow reversal and aspiration.
基底动脉闭塞是一种严重的临床事件,如果采用包括抗凝剂在内的标准药物治疗,患者死亡率很高。静脉注射组织型纤溶酶原激活剂或动脉内溶栓分别使30%-53%和64%的基底动脉卒中患者血管再通。机械血管内治疗可进行定制化操作,结果更快且再通率更高。作者描述了一名20岁男性患者,成功通过机械方法清除了基底动脉尖急性闭塞处的阻塞物,该阻塞涉及双侧大脑后动脉近端。他们同时使用了2个Merci取栓装置,并对双侧椎动脉近端进行闭塞以实现临时血流逆转和抽吸。