Yu Xu, Richard Seidu A, Fuhua Ye, Jianfeng Jiang, Xinmin Zhou, Min Wu
Department of Neurosurgery, Jiangyin Hospital, Southeast University, Jiangyin, Jiangsu 214400, P.R. China.
Department of Medicine, Princefield University, P.O. Box MA-128, Ho, Volta Region, Ghana.
Med Int (Lond). 2022 Oct 18;2(6):32. doi: 10.3892/mi.2022.57. eCollection 2022 Nov-Dec.
Acute ischemic stroke of the posterior circulation as a result of vertebrobasilar artery occlusions is often associated with severe morbidity and mortality rates. Vertebrobasilar artery occlusion retrieval via mechanical thrombectomy (MT) is a novel treatment modality for occlusive strokes. Nevertheless, factors associated with positive outcomes have not yet been adequately investigated. Thus, the present study focused on factors associated with good prognosis following this type of treatment. The present study retrospectively analyzed a series of 17 patients with acute vertebral artery occlusions (VAOs) and basilar artery occlusions (BAOs) treated with MT. In all patients, information such as sex and age, time from admission to the onset of femoral artery access, the number of thrombi removed, the time of femoral artery access to recanalization, pre- and post-operative National Institutes of Health Stroke Scale (NIHSS) scores, pre- and post-operative thrombolysis in cerebral infarction, as well as modified Rankin scale scores were documented and analyzed. The analysis comprised of 11 patients with BAOs and 6 patients with VAOs. A recanalization rate of 70.6% was achieved with an overall good functional outcome of 58.8% at 90 days. Observationally, there was a notable improvement in outcomes when comparing the NIHSS prior to surgery with NIHSS at 1 week after the surgery. A lower NIHSS score prior to MT may be a good prognostic factor. An average time of ~5.5 h from patient admittance to recanalization with a 70.6% recanalization rate with an overall good functional outcome of 58.8% at 90 days suggested that, patients for whom the surgeries were performed within 5 h of admittance may still have hope for recanalization compared to an initial 1.5-h average time for recanalization.
椎基底动脉闭塞导致的后循环急性缺血性卒中通常与严重的发病率和死亡率相关。通过机械取栓术(MT)进行椎基底动脉闭塞再通是一种治疗闭塞性卒中的新方法。然而,与良好预后相关的因素尚未得到充分研究。因此,本研究聚焦于此类治疗后与良好预后相关的因素。本研究回顾性分析了17例接受MT治疗的急性椎动脉闭塞(VAO)和基底动脉闭塞(BAO)患者。记录并分析了所有患者的性别、年龄、从入院到股动脉穿刺开始的时间、取出的血栓数量、从股动脉穿刺到再通的时间、术前和术后美国国立卫生研究院卒中量表(NIHSS)评分、术前和术后脑梗死溶栓情况以及改良Rankin量表评分。分析包括11例BAO患者和6例VAO患者。再通率达到70.6%,90天时总体良好功能预后率为58.8%。观察发现,将术前NIHSS评分与术后1周的NIHSS评分相比较,结果有显著改善。MT术前较低的NIHSS评分可能是一个良好的预后因素。从患者入院到再通的平均时间约为5.5小时,再通率为70.6%,90天时总体良好功能预后率为58.8%,这表明,与最初平均1.5小时的再通时间相比,在入院5小时内接受手术的患者仍可能有再通的希望。