Gras Daniel, Kubler Luc, Ritter Philippe, Anselme Frédéric, Delnoy Pierre Paul, Bordachar Pierre, Renesto Fabrizio, Mabo Philippe
Nouvelles Cliniques Nantaises, Nantes, France.
Pacing Clin Electrophysiol. 2009 Mar;32 Suppl 1:S240-6. doi: 10.1111/j.1540-8159.2008.02296.x.
The important role played by peak endocardial acceleration (PEA or sonR) in hemodynamic monitoring of cardiac resynchronization therapy (CRT) was recently highlighted in several studies with the sensor embedded in a right ventricular (RV) lead tip. This study examined the short- and long-term reliability of a right atrial (RA) sonR sensor.
RA and RV sonR signals were measured from RA and RV leads respectively, at implant and up to 12 months of follow-up, in 19 recipients of either single chamber pacemakers or CRT systems. At 1 month of follow up, RA sonR signals and heart rate were simultaneously recorded during exercise.
A reliable RA sonR signal amplitude was measured at implant, proportional to the RV amplitude. We observed in both the right atrium and right ventricle (1) a similar signal noise ratio at implant, (2) a similar evolution of the sonR signal amplitude up to 12 months of follow-up, and (3) a high correlation between heart rate and RA sonR signal amplitude during exercise.
The RA sonR signal was reliable and proportional to the RV signal on the short and long term, and reflected changes in activity. These observations suggest that the sonR sensor could be placed in the atrium for the hemodynamic monitoring of CRT system recipients.
近期多项研究强调了峰内膜加速度（PEA或sonR）在心脏再同步治疗（CRT）血流动力学监测中所起的重要作用，这些研究中传感器嵌入右心室（RV）导线尖端。本研究检测了右心房（RA）sonR传感器的短期和长期可靠性。
在19名单腔起搏器或CRT系统植入者中，分别于植入时及随访长达12个月时，从RA和RV导线测量RA和RV的sonR信号。在随访1个月时，运动期间同时记录RA sonR信号和心率。
植入时测量到可靠的RA sonR信号幅度，与RV幅度成比例。我们在右心房和右心室均观察到：（1）植入时类似的信号噪声比；（2）随访长达12个月时sonR信号幅度的类似变化；（3）运动期间心率与RA sonR信号幅度之间的高度相关性。
RA sonR信号在短期和长期均可靠且与RV信号成比例，并反映活动变化。这些观察结果表明，对于CRT系统植入者，sonR传感器可置于心房用于血流动力学监测。
