Oosterman Joukje M, van Someren Eus J W, Vogels Raymond L C, Van Harten Barbera, Scherder Erik J A
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands.
J Sleep Res. 2009 Mar;18(1):129-35. doi: 10.1111/j.1365-2869.2008.00704.x.
Aging affects both cognitive performance and the sleep-wake rhythm. The recent surge of studies that support a role of sleep for cognitive performance in healthy young adults suggests that disturbed sleep-wake rhythms may contribute to 'age-related' cognitive decline. This relationship has however not previously been extensively investigated. The present correlational study integrated a battery of standardized cognitive tests to investigate the association of mental speed, memory, and executive function with actigraphically recorded sleep-wake rhythms in 144 home-dwelling elderly participants aged 69.5 +/- 8.5 (mean +/- SD). Multiple regression analyses showed that the partial correlations of the fragmentation of the sleep-wake rhythm with each of the three cognitive domains (r = -0.16, -0.19, and -0.16 respectively) were significant. These associations were independent from main effects of age, implying that a unique relationship between the rest-activity rhythm and cognitive performance is present in elderly people.
衰老会影响认知表现和睡眠-觉醒节律。最近大量研究表明，睡眠对健康年轻成年人的认知表现有作用，这表明睡眠-觉醒节律紊乱可能导致“与年龄相关的”认知衰退。然而，这种关系此前尚未得到广泛研究。本相关性研究整合了一系列标准化认知测试，以调查144名年龄在69.5±8.5岁（平均±标准差）的居家老年人的心理速度、记忆和执行功能与通过活动记录仪记录的睡眠-觉醒节律之间的关联。多元回归分析表明，睡眠-觉醒节律碎片化与三个认知领域中每一个领域的偏相关性（分别为r = -0.16、-0.19和-0.16）均显著。这些关联独立于年龄的主要影响，这意味着老年人的休息-活动节律与认知表现之间存在独特关系。
