Sweileh Waleed M, Sawalha Ansam F, Zyoud Sa'ed H, Al-Jabi Samah W, Abaas Majd A
College of Pharmacy, An-Najah National University, Nablus, Palestine.
J Stroke Cerebrovasc Dis. 2009 Mar-Apr;18(2):97-102. doi: 10.1016/j.jstrokecerebrovasdis.2008.08.005.
The aim of this study was to analyze the types and cost of medications prescribed at discharge for ischemic stroke survivors.
This is a descriptive study of medications prescribed for ischemic stroke survivors admitted to Al-watani hospital during a 6-month period.
A total of 95 consecutive stroke patients were included in the study period; 78 (82.1%) survivors were having ischemic stroke subtype and were designated the study group. The average age of the survivors was 66.9 +/- 12.7 years. Survivors had prevalent risk factors such as diabetes mellitus (70%), hypertension (68%), and ischemic heart disease (34.6%). On average, survivors experienced a minimum of 0.73 complications (range 0-3) with the most common being infections (n = 35, 44.8%). Forty-two per cent of the ischemic stroke survivors were taking antiplatelet drugs prior to the current attack. At discharge, ischemic stroke survivors were prescribed an average of 4.9 medications from 4.3 different drug classes. All ischemic stroke survivors were prescribed antiplatelet therapy at discharge. Aspirin monotherapy was prescribed for 61 survivors while the combination of aspirin/clopidogrel antiplatelet therapy was prescribed for 17 survivors. The average monthly cost for prophylactic therapy and for medications used to treat post-stroke complication was approximately 52 USD per survivor.
Most of the patients in the study group were having the traditional risk factors for ischemic stroke and were suffering form typical post-stroke complications. Lack of medical insurance will impose a heavy financial burden on stroke survivors in Palestine.
本研究旨在分析缺血性中风幸存者出院时所开药物的类型和费用。
这是一项对在6个月期间入住阿尔瓦塔尼医院的缺血性中风幸存者所开药物的描述性研究。
在研究期间共纳入95例连续的中风患者；78例（82.1%）幸存者为缺血性中风亚型，被指定为研究组。幸存者的平均年龄为66.9±12.7岁。幸存者存在常见的危险因素，如糖尿病（70%）、高血压（68%）和缺血性心脏病（34.6%）。平均而言，幸存者至少经历0.73种并发症（范围为0 - 3种），最常见的是感染（n = 35，44.8%）。42%的缺血性中风幸存者在本次发作前正在服用抗血小板药物。出院时，缺血性中风幸存者平均从4.3种不同药物类别中开具了4.9种药物。所有缺血性中风幸存者出院时均被开具抗血小板治疗药物。61例幸存者被开具阿司匹林单药治疗，17例幸存者被开具阿司匹林/氯吡格雷联合抗血小板治疗。每位幸存者预防性治疗和用于治疗中风后并发症的药物平均每月费用约为52美元。
研究组中的大多数患者具有缺血性中风的传统危险因素，并患有典型的中风后并发症。缺乏医疗保险将给巴勒斯坦的中风幸存者带来沉重的经济负担。
