Yang Chwen-Yi, Chou Chien-Wen, Lin Ming-Bin, Li Chien-Feng
Division of Endocrinology and Metabolism, Department of Medicine, Chi-Mei Hospital, Tainan, Taiwan, ROC.
J Chin Med Assoc. 2009 Feb;72(2):83-7. doi: 10.1016/S1726-4901(09)70028-0.
Schwannoma is a rare tumor of neural crest cell origin. Most schwannomas occur in the head, neck, stomach or limbs, with a few cases occurring in the retroperitoneal space. A 30-year-old Taiwanese woman presented with a 1-week history of left anterior chest discomfort and left flank pain. The laboratory findings and endocrine studies were all within normal limits. Chest X-ray revealed masses in the posterior mediastinum. Chest computed tomography and magnetic resonance imaging showed several masses in the left paraspinal region and in the left adrenal region. The patient underwent total excision of the left paraspinal tumors and laparoscopic left adrenalectomy. Pathologic studies showed a picture of benign schwannoma. In conclusion, preoperative differentiation of benign schwannoma from malignant peripheral nerve sheath tumor or other tumors is important for good prognosis. Total excision of benign schwannoma is associated with favourable outcome in patients.
施万细胞瘤是一种起源于神经嵴细胞的罕见肿瘤。大多数施万细胞瘤发生于头、颈、胃或四肢，少数病例发生于腹膜后间隙。一名30岁的台湾女性，有1周的左前胸不适和左侧胁腹疼痛病史。实验室检查结果和内分泌研究均在正常范围内。胸部X线显示后纵隔有肿块。胸部计算机断层扫描和磁共振成像显示左椎旁区域和左肾上腺区域有多个肿块。患者接受了左椎旁肿瘤全切术和腹腔镜下左肾上腺切除术。病理研究显示为良性施万细胞瘤。总之，术前将良性施万细胞瘤与恶性周围神经鞘膜瘤或其他肿瘤区分开来对良好预后很重要。良性施万细胞瘤全切术对患者有良好的预后。
