Reimers Jeffrey R, McKemmish Laura K, McKenzie Ross H, Mark Alan E, Hush Noel S
School of Chemistry, University of Sydney, Sydney, New South Wales 2006 Australia.
Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4219-24. doi: 10.1073/pnas.0806273106. Epub 2009 Feb 26.
In 1968, Fröhlich showed that a driven set of oscillators can condense with nearly all of the supplied energy activating the vibrational mode of lowest frequency. This is a remarkable property usually compared with Bose-Einstein condensation, superconductivity, lasing, and other unique phenomena involving macroscopic quantum coherence. However, despite intense research, no unambiguous example has been documented. We determine the most likely experimental signatures of Fröhlich condensation and show that they are significant features remote from the extraordinary properties normally envisaged. Fröhlich condensates are classified into 3 types: weak condensates in which profound effects on chemical kinetics are possible, strong condensates in which an extremely large amount of energy is channeled into 1 vibrational mode, and coherent condensates in which this energy is placed in a single quantum state. Coherent condensates are shown to involve extremely large energies, to not be produced by the Wu-Austin dynamical Hamiltonian that provides the simplest depiction of Fröhlich condensates formed using mechanically supplied energy, and to be extremely fragile. They are inaccessible in a biological environment. Hence the Penrose-Hameroff orchestrated objective-reduction model and related theories for cognitive function that embody coherent Fröhlich condensation as an essential element are untenable. Weak condensates, however, may have profound effects on chemical and enzyme kinetics, and may be produced from biochemical energy or from radio frequency, microwave, or terahertz radiation. Pokorný's observed 8.085-MHz microtubulin resonance is identified as a possible candidate, with microwave reactors (green chemistry) and terahertz medicine appearing as other feasible sources.
1968年,弗勒利希指出,一组受驱动的振荡器能够凝聚,几乎所有提供的能量都会激活最低频率的振动模式。这是一种显著的特性,通常可与玻色 - 爱因斯坦凝聚、超导、激光以及其他涉及宏观量子相干的独特现象相比较。然而,尽管进行了深入研究,但尚未有明确的实例被记录在案。我们确定了弗勒利希凝聚最可能的实验特征,并表明它们是远离通常所设想的非凡特性的显著特征。弗勒利希凝聚体可分为3种类型:可能对化学动力学产生深远影响的弱凝聚体、将极大量能量导入一种振动模式的强凝聚体,以及将该能量置于单个量子态的相干凝聚体。研究表明,相干凝聚体涉及极大的能量,并非由提供了对利用机械供应能量形成的弗勒利希凝聚体最简单描述的吴 - 奥斯汀动力学哈密顿量产生,并且极其脆弱。它们在生物环境中无法实现。因此,将相干弗勒利希凝聚作为基本要素的彭罗斯 - 哈梅罗夫精心策划的客观还原模型及相关认知功能理论是站不住脚的。然而,弱凝聚体可能对化学和酶动力学产生深远影响,并且可能由生化能量或射频、微波或太赫兹辐射产生。波科尔尼观察到的8.085兆赫微管蛋白共振被确定为一个可能的候选者,微波反应器(绿色化学)和太赫兹医学则是其他可行的来源。