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前交叉韧带重建手术时机与软骨损伤及半月板撕裂风险:一项基于挪威国家膝关节韧带登记处的队列研究。

Timing of anterior cruciate ligament reconstructive surgery and risk of cartilage lesions and meniscal tears: a cohort study based on the Norwegian National Knee Ligament Registry.

作者信息

Granan Lars-Petter, Bahr Roald, Lie Stein Atle, Engebretsen Lars

机构信息

Oslo Sports Trauma Research Center, Norwegian School of Sport Sciences, Oslo, Norway.

出版信息

Am J Sports Med. 2009 May;37(5):955-61. doi: 10.1177/0363546508330136. Epub 2009 Feb 26.

Abstract

BACKGROUND

There is inadequate evidence to determine when to perform surgery on anterior cruciate ligament-deficient knees.

PURPOSE

To study the association between timing of anterior cruciate ligament reconstruction and the risk of having meniscal tears and cartilage lesions.

STUDY DESIGN

Cohort study (prognosis); Level of evidence, 2.

METHODS

All patients registered in the Norwegian National Knee Ligament Registry who had undergone primary anterior cruciate ligament reconstruction from 2004 and throughout 2006 were reviewed. Logistic regression analyses were used to estimate the relationship between time from injury until anterior cruciate ligament surgery and the risk of meniscal tears or cartilage lesions.

RESULTS

Of a total of 3475 patients, there were 909 patients (26%) with cartilage lesions, 1638 patients (47%) with meniscal tears, and 527 patients (15%) with both cartilage and meniscal lesions. The odds of a cartilage lesion in the adult knee (>16 years) increased by 1.006 (95% confidence interval, 1.003-1.010) for each month that elapsed from injury to surgery. The cartilage in young adults (17-40 years) deteriorated further with an increase in odds of 1.03 (95% confidence interval, 1.02-1.05) related to the aging in years of the patient. The odds for meniscal tears in young adults increased by 1.004 (95% confidence interval, 1.002-1.006) for each month that elapsed since injury. The presence of 1 degenerative lesion increased the odds of having the other degenerative lesion by between 1.6 and 2.0 in all patient groups.

CONCLUSION

The odds of a cartilage lesion in the adult knee increased by nearly 1% for each month that elapsed from the injury date until the surgery date and that of cartilage lesions were nearly twice as frequent if there was a meniscal tear, and vice versa.

摘要

背景

尚无足够证据确定何时对前交叉韧带损伤的膝关节进行手术。

目的

研究前交叉韧带重建时机与半月板撕裂和软骨损伤风险之间的关联。

研究设计

队列研究(预后);证据等级,2级。

方法

回顾了挪威国家膝关节韧带登记处登记的所有在2004年至2006年期间接受初次前交叉韧带重建的患者。采用逻辑回归分析来估计从受伤到前交叉韧带手术的时间与半月板撕裂或软骨损伤风险之间的关系。

结果

在总共3475例患者中,有909例(26%)存在软骨损伤,1638例(47%)存在半月板撕裂,527例(15%)同时存在软骨和半月板损伤。从受伤到手术每过去一个月,成年膝关节(>16岁)发生软骨损伤的几率增加1.006(95%置信区间,1.003 - 1.010)。年轻成年人(17 - 40岁)的软骨随着患者年龄增长几率进一步增加,增加幅度为1.03(95%置信区间,1.02 - 1.05)。自受伤以来每过去一个月,年轻成年人半月板撕裂的几率增加1.004(95%置信区间,1.002 - 1.006)。在所有患者组中,存在1种退行性病变会使发生另一种退行性病变的几率增加1.6至2.0倍。

结论

从受伤日期到手术日期每过去一个月,成年膝关节发生软骨损伤的几率增加近1%,如果存在半月板撕裂,软骨损伤的发生率几乎会翻倍,反之亦然。

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