Tondeur Marianne C, De Palma Diego, Roca Isabel, Piepsz Amy, Ham Hamphrey H
Department of Radioisotopes, CHU St Pierre, Brussels, Belgium.
Nucl Med Commun. 2009 Apr;30(4):258-62. doi: 10.1097/MNM.0b013e328318b33f.
To evaluate the interobserver reproducibility in reporting on technetium-99m (99mTc) dimercaptosuccinic acid (DMSA) scan in children.
Sixty 99mTc-DMSA scans, issued from three centres, were distributed by e-mail to nuclear medicine physicians from the five continents interested in paediatric nuclear medicine. Observers had to choose, for each kidney, among four answers: normal, abnormal, equivocal or poor quality. An additional question was the location of the lesion if any: upper part, mid part, lower part. The responses had to be returned by e-mail.
Sixty-one observers, with an experience of approximately five or more 99mTc-DMSA/month, contributed to the study. Median agreement was 93%. The agreement was less than 80% in 29 kidneys (24%) but only in 13% (16 kidneys) was there disagreement between normality and abnormality, the remaining cases being related to 'equivocal' responses. Disagreement was mainly related to the following patterns: (i) normal variants: pear-shaped kidney, hypoactive poles contrasting with important parenchymal mass, triangular kidney, unusual shape of the columns of Bertin; (ii) congenital abnormalities: hydronephrosis, normal duplex kidney; (iii) small defects.
Interobserver reproducibility can be considered as good among a wide number of observers from the five continents. Disagreement among observers could be reduced by taking the normal variants into account.
评估儿童99m锝(99mTc)二巯基丁二酸(DMSA)扫描报告中观察者间的可重复性。
来自三个中心的60份99mTc-DMSA扫描图像通过电子邮件分发给五大洲对儿科核医学感兴趣的核医学医师。观察者必须针对每个肾脏从以下四个答案中选择:正常、异常、可疑或质量差。如果有病变,还需回答病变的位置:上部、中部、下部。答案需通过电子邮件返回。
61名观察者参与了该研究,他们每月至少有5次99mTc-DMSA扫描的经验。中位数一致性为93%。29个肾脏(24%)的一致性低于80%,但只有13%(16个肾脏)在正常与异常判断上存在分歧,其余情况与“可疑”反应有关。分歧主要与以下情况有关:(i)正常变异:梨形肾、与重要实质肿块形成对比的低活性极、三角形肾、贝尔廷柱形状异常;(ii)先天性异常:肾积水、正常重复肾;(iii)小缺损。
五大洲众多观察者之间的观察者间可重复性可认为良好。考虑正常变异可减少观察者之间的分歧。